The invention relates to a guiding and vibration-isolating coupled seat for a vehicle. The left and right sides of the structure are symmetrical, and one side thereof includes: a seat panel connected in sequence, a scissor mechanism, a shock absorber, a main spring, a seat bottom plate, and a connecting seat. Rod, auxiliary spring cover, auxiliary spring, auxiliary spring base, wherein, the scissor mechanism, connecting rod, auxiliary spring base, auxiliary spring, auxiliary spring cover, seat panel and seat bottom plate together constitute the scissor negative stiffness Vibration isolation mechanism, which has the function of guiding the vertical motion of the seat and the function of negative stiffness vibration isolation. Effective low-frequency vibration isolation is achieved through the joint action of the main spring, shock absorber and scissor-type negative stiffness vibration isolation mechanism. At the same time, the vertical movement of the seat is more stable; Seats are fairly vibration-isolating. The seat of the invention is simple and compact in structure, uses few parts, is easy to install, has stable performance, low cost, good vibration isolation effect and reliability, and is suitable for vehicles such as trucks, armored vehicles, rail vehicles and engineering vehicles.