The invention relates to a travel safety evaluation method and a system based on multi-source spatio-temporal data. The method of the invention comprises the following steps: data collection and pretreatment, road segment division, map matching, and multi-dimensional safety index calculation. The system of the invention comprises a multi-source spatio-temporal data analysis platform, a geographical server, a government terminal, an enterprise terminal, a driver terminal and a passenger terminal. Compared with the existing static supervisory system based on identity attributes, the invention, based on multi-source spatio-temporal data mining, multi-dimensional analysis of road safety and driver safety in each section of the road at each time, can more accurately evaluate the safety level ofcar-sharing travel, and with the help of safety index to quantify the risk of car-sharing travel, and innovates the regulatory system, which is an important embodiment of the modernization of governance system and governance capacity, can improve the efficiency of government management, achieve dynamic supervision of enterprises, regulate driver driving behavior, and assist passenger travel decision-making.