This invention relates to a portable measurement, analysis and diagnosis apparatus applied to medicine, biological medicine and chemistry, which comprises a sample tray, a housing forming apparatus bottom bracket, an image acquisition system acquiring sample image information, a data process and display unit of general minicomputer comprising a hand-held computer, a pocket personal computer, a personal digital assistant, palmtop computer and laptop computer, or general microprocessor and special support hardware, which is used to measure, analyze and diagnose said sample according to said image information.