The invention relates to a transverse isotropy stratum elastic coefficient well logging calculation method and device. The method comprises the steps that coring in different directions is carried out on a rock core, and a rock core sample is obtained; the rock core sample is measured, the longitudinal wave speed and the transverse wave speed of the rock core sample are obtained, and elastic coefficients C11, C13, C33, C44 and C66 are obtained by calculation of the longitudinal wave speed and the transverse wave speed; the elastic coefficients C33, C44 and C66 are obtained through array acoustic logging data and density logging data of a coring well; a combination relational expression between the measurable logging elastic coefficients C33, C44 and C66 and the unmeasurable logging elastic coefficients C11 and C13 is built by the utilization of the elastic coefficients C11, C13, C33, C44 and C66 obtained by calculation of the longitudinal wave speed and the transverse wave speed; the elastic coefficients C33, C44 and C66 obtained through the array acoustic logging data and the density logging data of the coring well are substituted to the combination relational expression, the unmeasurable logging elastic coefficients C11 and C13 are obtained, and finally the elastic coefficients representing the transverse isotropy stratum are obtained.