59 results about "Ultrasound method" patented technology

The invention relates to the technical field of material mechanical property testing, in particular to a method for measuring residual stress of a metal component. According to the technical scheme, the method for measuring the residual stress of the metal component comprises a working process for measuring the residual stress of the metal component; according to the method, a technical path of multi-modal data assimilation is adopted, and a mechanical release mechanism of a drilling method and an ultrasonic stress measurement technology are deeply fused to calibrate and correct mass sound velocity data obtained by carrying out rapid ultrasonic scanning on the whole component on site, so that the precise measurement of the residual stress state of the metal component is realized, and the measurement precision is improved. According to the method, data authority and high credibility of a drilling method in a key area are reserved, the advantages of high efficiency and wide coverage of full-field measurement of an ultrasonic method are brought into full play, and efficient and accurate stress information is provided on the premise that components are not excessively damaged.

The invention discloses a preparation method and application of a dual-targeting carrier-free delivery system for enhancing anti-tumor immunity of NKT cells, Lys-alpha-GalCer is used as a raw material, and two molecules of LGC are connected through a disulfide bond to synthesize an amphiphilic LGC-SS-LGC micromolecule prodrug; the LGC-SS-LGC micromolecule prodrug is prepared into vesicles internally loaded with an NKT cell antigen presenting molecule CD1d and externally modified with polysarcosine through electrostatic adsorption through a film dispersion-probe ultrasonic method, finally a CD1d / LGC-SS-LGC / PSar dual-targeting carrier-free delivery system is formed, and the dual-targeting carrier-free delivery system can be used for liver cancer treatment after intravenous administration. In addition, the compound can be used for preparing a preparation for enhancing NKT cell Th1 type immune response. The dual-targeting carrier-free delivery system prepared by the invention can directly or indirectly enhance the anti-tumor immune effect of the NKT cells, and has a dual-synergistic effect.

A computer-implemented method of automatically identifying a reference vessel in an ultrasound image, the method comprising: segmenting the image to identify an organ; locating a predetermined anatomical landmark specific to the organ; identifying appropriate vasculature for the organ; and selecting a reference vessel from the vasculature that has a size within a predetermined size range and a location with a predetermined distance range from the predetermined interface.

A method of producing cytopathologic cell samples, the method including insonating a target tissue by ultrasound energy with a focused beam at that generates shear waves within the tissue. A method of producing cytopathologic cell samples, the method including insonating a target tissue by ultrasound energy at a first intensity level during a first period, insonating the target tissue by ultrasound energy at a second intensity level during a second period, wherein the first intensity level is higher than the second intensity level. Related apparatus and methods are also described.

The invention relates to the technical field of ovarian cancer cell membrane modification, and discloses an ovarian cancer cell membrane modified co-loaded DOX / IND nanoparticle and a preparation method thereof.The ovarian cancer cell membrane modified co-loaded DOX / IND nanoparticle comprises IND, DOX and ID8 cell membranes, and the preparation method comprises the following steps that 1, DOX / IND (at) cmLPs is prepared, a film dispersion ultrasonic method and an ammonium sulfate gradient method are adopted for constructing a co-loaded DOX / IND liposome, and the liposome is used for preparing the ovarian cancer cell membrane modified co-loaded DOX / IND nanoparticle; the method comprises the following steps: (1) preparing an ovarian cancer cell membrane by adopting a gradient centrifugation method, (2) preparing the ovarian cancer cell membrane by adopting a gradient centrifugation method, (3) preparing ovarian cancer cell membrane fused Indoximod and DOX co-loaded lipidosome (DOX / IND (at) cmLPs), and (4) detecting and verifying the characterization of the DOX / IND (at) cmLPs. According to the ovarian cancer cell membrane modified co-loaded DOX / IND nanoparticle and the preparation method thereof, a liposome co-loaded with DOX / IND is constructed by adopting a thin film dispersion ultrasonic method and an ammonium sulfate gradient method, the technical bottleneck of DOX / IND co-loading is solved through process optimization, and the ovarian cancer cell membrane modified co-loaded DOX / IND nanoparticle has the characteristics of high encapsulation efficiency, synergistic curative effect and intelligent release; a new thought is provided for combined treatment of drug-resistant tumors such as ovarian cancer.

A method of producing cytopathologic cell samples, the method including insonating a target tissue by ultrasound energy with a focused beam at that generates shear waves within the tissue. A method of producing cytopathologic cell samples, the method including insonating a target tissue by ultrasound energy at a first intensity level during a first period, insonating the target tissue by ultrasound energy at a second intensity level during a second period, wherein the first intensity level is higher than the second intensity level. Related apparatus and methods are also described.

The invention discloses a composite exosome encapsulating linear macromolecular nanoparticles as well as a preparation method and application thereof, and belongs to the technical field of biological materials and regenerative medicine. Aiming at the pain points that in the prior art, when linear macromolecules such as collagen and hyaluronic acid are encapsulated by exosomes, the encapsulation efficiency is low, the structure of the exosomes is easy to damage, and the molecular weight adaptability is poor, the invention provides the preparation method which comprises the following steps: firstly, pretreating the collagen of 5 kDa to 330 kDa and the hyaluronic acid of 10 kDa to 2200 kDa into dense nanoparticles of 10 to 150 nm and PDI less than or equal to 0.15 through a nanoprecipitation method, an electrostatic complexation method and the like; and encapsulating in the exosome through an electroporation method, a freeze-thaw cycle method or an ultrasonic method, and purifying to obtain the composite exosome. According to the method, linear macromolecules with different molecular weights are adapted by flexibly adjusting process parameters, the encapsulation efficiency is remarkably improved, and the membrane structure of the exosome can be kept complete. The obtained composite exosome has the signal transduction function of the exosome and the biological activity of linear macromolecules, and generates a synergistic effect in tissue repair.

Ultrasound methods and systems for measuring physiological properties are disclosed. The ultrasound methods and systems measure one or more characteristics of a vessel, such as vessel-wall displacement over time or blood-flow velocity over time, based on a pulse wave propagating through the vessel. In aspects, the characteristics are measured at two locations of the same vessel with a known distance between the two locations. A time shift between the measured characteristics at the two locations is calculated and used, along with the known distance, to determine one or more physiological properties, such as pulse-wave velocity or blood pressure. These physiological properties can be measured without the assistance of ECG data.

The application discloses a cellulose-based composite material for simultaneously removing copper and tetracycline from water bodies and a preparation method thereof, and belongs to the technical field of environmental functional composite materials. The cellulose-based composite material is Zr-MOF / CNF, and the specific preparation steps include the following steps: first, a zirconium (Zr)-based MOF is prepared by using an ultrasonic method; then, nanocellulose is prepared by using a TEMPO oxidation method; and finally, the obtained white suspension liquid is mixed under ultrasonic assistance, centrifuged, washed with water and washed with alcohol, so as to obtain a Zr-MOF / CNF composite material. The material is synthesized by using the ultrasonic method, the preparation process is simple, the raw material cost is low, and the problems of the cellulose, such as the lack of a porous structure, the MOF particle agglomeration and the poor water stability, are improved, and the practical application capability of the Zr-MOF / CNF is improved. The cellulose-based composite material can effectively adsorb copper and tetracycline, when the initial concentrations of the copper and the tetracycline are 32 mg / L and 444 mg / L respectively, and the initial solution pH is 7.0, the adsorption capacities of the Zr-MOF / CNF for the copper and the tetracycline are 157.08 mg / g and 1532 mg / g respectively.

A system and method for human heart modelling to create a dynamic virtual model of heart that can be used for diagnosis and determining suitable therapy. The dynamic virtual model can be created using 2D or 3D echo images or video clips obtained from ultrasound reversal wave data. Arbitrary pixels or voxels in the echo images are tracked phase-by-phase per cardiac cycle. From this, original reversal wave equation ρp attached to the arbitrary pixel or voxel is obtained. Then is generated a deformable map fp with an equation of curve passed from the arbitrary pixel or voxel within the cardiac cycle determined by solving Lagrange-Euler equations. Finally, new 2D or 3D images with improved spatial resolution can be obtained that are used for the human heart modelling.

The invention provides a particle size detection method of silica powder. The particle size detection method comprises the following steps: carrying out surface modification on the silica powder by adopting a silane coupling agent containing a polyethylene glycol chain segment, and carrying out particle size detection on the surface-modified silica powder. After the silane coupling agent containing the polyethylene glycol chain segment is adopted to perform surface modification on the silica powder, and a long-chain hydrophilic chain segment is chemically grafted on the surface of the silica powder, the silica powder obtains self-emulsifying dispersing capacity, and the dispersity and stability of the silica powder in dispersion liquid are greatly improved. Compared with an ultrasonic method, an external emulsification method and the like, the influence of external factors such as a sampling mode and an ultrasonic condition on the particle size detection result measured by the method is greatly reduced, and the test result is more accurate and stable.

Methods and systems are disclosed for employing an ultrasonic sensor to estimate a range for a moving object. At least one processor separates returned signals received by an ultrasonic transducer into a stationary object signal and a moving object signal. A gain is determined based at least in part on the stationary object signal. The stationary object signal is combined with the moving object signal using the gain and then filtered. The range for the moving object is estimated using the filtered combined stationary and moving object signal.

This invention relates to the field of non-destructive testing technology in building engineering, and discloses a comprehensive method for testing concrete strength based on the rebound method and ultrasonic method. The method includes: acquiring the full-wavelength ultrasonic signal of the test area and calculating the propagation velocity; performing a rebound impact in the test area to obtain the rebound value and acceleration sequence, analyzing and defining the impact contact time and calculating the initial energy absorption ratio; mapping the impact contact time to a cutoff frequency, and performing frequency band integration on the full-wavelength ultrasonic signal to obtain the dispersion attenuation coefficient; comparing the dispersion attenuation coefficient with a scattering threshold, and establishing the initial energy absorption ratio or pure mortar phase characteristics as a mechanical feature set based on the results; converging the propagation velocity, rebound value, impact contact time, dispersion attenuation coefficient, and mechanical feature set to construct an initial comprehensive state matrix; extracting orthogonal principal component latent variables from this matrix and performing quantized superposition to output the concrete compressive strength. This invention eliminates parameter multicollinearity and improves detection accuracy by establishing a physical correlation between mechanical impact and the ultrasonic frequency domain.

This invention discloses a non-contact laser-ultrasound method and system for detecting internal defects in high-entropy alloys. The method first pre-treats the surface of the high-entropy alloy sample, then adaptively adjusts the laser pulse parameters according to the thermal conductivity characteristics of the high-entropy alloy to excite internal ultrasonic waves via thermoelastic effects. After non-contact signal reception using a laser interferometer, signal pre-processing is performed using a wavelet packet transform and principal component analysis fusion algorithm. Defect features are then extracted using a local outlier factor and support vector machine fusion algorithm to distinguish between defects and lattice distortion interference signals. Defect parameters are analyzed using an improved ultrasonic propagation model, combining mechanical parameters and lattice distortion coefficients. Finally, cross-validation and error correction ensure detection accuracy. The system comprises seven modules, including sample pre-processing, laser excitation, and ultrasonic reception, with a main control module coordinating the collaborative work of each module. This invention achieves non-contact detection, improving detection adaptability and accuracy, and enabling automated batch online detection.

This invention discloses a Co 0.2 Cd 0.8 This paper describes the preparation method of S / CaTiO3 / NiSx materials and their application in photocatalytic nitrogen fixation, belonging to the field of photocatalytic materials technology. Firstly, an S-type heterostructure Co was prepared using an ultrasonic method. 0.2 Cd 0.8 S / CaTiO3 composite, then using ultrasound to bond metalloid NiS x Nanoparticle co-catalysts and Co 0.2 Cd 0.8 S / CaTiO3 complex forms Co 0.2 Cd 0.8 S / CaTiO3 / NiS x Ternary composite photocatalyst. The semiconductor Co in this invention... 0.2 Cd 0.8 S and semiconductor CaTiO3 first form an S-type heterostructure, which not only accelerates the directional movement and separation of photogenerated electrons and holes, but also maintains the strong redox capability of photogenerated charge carriers; in addition, NiS is loaded onto the S-type heterostructure. x co-catalyst, NiS x Nanoparticle co-catalysts, acting as electron-capturing centers, can not only provide more reactive sites but also further improve charge separation efficiency.

The invention relates to the technical field of aero-engine split casing notch prediction, in particular to a residual stress-based ring axial notch distortion prediction method and a residual stress-based ring axial notch distortion prediction model. Comprising the following steps: performing residual stress detection on inner and outer ring surfaces of a ring piece by adopting a blind hole method / ultrasonic method / contour method and the like; calculating the bending moment of the ring piece; calculating an unloading bending moment; calculating stress change after unloading; calculating the angle change after unloading; calculating the distance change after unloading; according to the invention, the incision distortion amount can be accurately predicted in advance; efficiency is improved, the research and development cycle is shortened, and repeated trial cutting is not needed; according to a traditional method, notch distortion needs to be verified through multiple machining tests, and a large amount of time and materials are consumed; direct calculation is carried out through a theoretical model, and the trial and error cost is greatly reduced.

An ultrasonic method for perfusion monitoring, comprising the steps of: acquiring an ultrasonic signal of a biological tissue; extracting a corresponding ultrasonic blood flow signal derived from the moving red blood cells from the ultrasonic signal; determining the intensity of the ultrasonic blood flow signal; determining intensity distribution of the ultrasonic blood flow signals; determining a current perfusion parameter value representative of a perfusion in the biological tissue based on the determined intensity profile of the ultrasonic blood flow signal; estimating a reference perfusion parameter value representative of perfusion in the biological tissue in a normal state based on at least one reference intensity profile of the ultrasonic blood flow signal; determining at least one critical perfusion parameter threshold based on the reference perfusion parameter value; and iteratively monitoring perfusion in the plurality of blood vessels by comparing the current perfusion parameter value to the at least one critical perfusion parameter threshold.

This application discloses an adjustable focal zone focusing ultrasound method, a piezoelectric metasurface preparation method, and a system, relating to the field of electro-digital data processing. The method includes: determining key parameters of the Airy wave function based on the shape and size of the target focal region; determining the phase distribution of each piezoelectric unit based on the key parameters of the Airy wave function to form a binary phase distribution; preparing a piezoelectric metasurface with a binary phase distribution; and using the piezoelectric metasurface to achieve ultrasonic focusing. This application enables customized ultrasonic focusing according to different application requirements, improving applicability and flexibility. Simultaneously, this application enables precise control of the ultrasonic wave phase, greatly simplifying the structure of the application system, reducing manufacturing and maintenance costs, and improving the reliability and stability of the application system. This fills the technological gap of being unable to flexibly adjust FLHW and FWHW under low cost and without electrical control.

This invention discloses a method and apparatus for measuring the liquid level amplitude of a pulse extraction column. The method includes: at a test bench, selecting either ultrasonic or direct measurement of the liquid level amplitude of the pulse extraction column, recording the amplitude measurement results and their corresponding adjustable factors, forming a coordinate point set Y; and using the air blowing method to measure the liquid level amplitude of the pulse extraction column under the same conditions, recording the amplitude measurement results and their corresponding adjustable factors, forming a coordinate point set X; calculating the relationship between Y and X to obtain the transformation matrix M from X to Y; in actual engineering, using the air blowing method to measure the liquid level amplitude of the pulse extraction column, and recording the amplitude measurement results and their corresponding adjustable factors, forming a coordinate point set X1; and calculating the pulse extraction column amplitude in actual engineering based on the transformation matrix M and X1. This invention can optimize the results of existing air blowing methods for measuring pulse extraction columns, reducing interference from various factors in the measurement environment and reducing amplitude measurement errors.

Magnetic resonance and ultrasound methods can produce estimates of full rank-4 elasticity tensors (E-tensors) using suitable constraints. E-tensor estimates can be based on E-tensor symmetry conditions and a suitable E-tensor selected from among a set of E-tensors calculated using different symmetry constraints. Displacement fields used in E-tensor calculations can be noise reduced using compatibility conditions. With the selected E-tensor, various stains that are rotation invariant can be computed. In one example, an E-tensor for an in vivo brain is computed using the mechanical disturbance associated with cardiac pulsations. The selected E-tensor and associated stains, physiological disorders such as Alzheimer's disease and traumatic brain injury (TBI) and even neural activation may be more readily detected than with conventional methods that do not use the full E-tensor.

This invention belongs to the field of two-dimensional graphene oxide nanomaterial technology. This invention provides a method for separating the size of monolayer graphene oxide, comprising the following steps: mixing water and an organic solvent and allowing the mixture to stand to obtain an oil / water two-phase system containing an oil phase and an aqueous phase; adding a surfactant and an aqueous solution of monolayer graphene oxide to the oil phase and the aqueous phase respectively, allowing the mixture to stand, repeatedly collecting the oil-water interface layer solution, and sequentially washing and centrifuging the interface layer solution to obtain large-sized monolayer graphene oxide; centrifuging the remaining aqueous phase solution to obtain small-sized monolayer graphene oxide. The method for separating the size of monolayer graphene oxide of this invention has good separation accuracy; and compared with ultrasonic methods, centrifugation methods, and membrane filtration methods, it has milder reaction conditions, lower energy consumption, and does not cause changes in the structure and size of graphene oxide; compared with precipitation methods and liquid crystal methods, the reaction time is shorter; and compared with electrophoresis methods, it does not change the structure of graphene oxide.

The application discloses a kind of Mn 0.5 Cd 0.5 Preparation method of S / CaTiO3 / Ni3C material and its application in photocatalytic nitrogen fixation, belong to the technical field of photocatalytic material. First, Mn 0.5 Cd 0.5 S / CaTiO3 S type heterostructure is prepared by in-situ deposition method, then the metalloid Ni3C nano-particle cocatalyst is combined with Mn 0.5 Cd 0.5 S / CaTiO3 by ultrasonic method to form Mn 0.5 Cd 0.5 S / CaTiO3 / Ni3C ternary composite photocatalyst. In the application, semiconductor Mn 0.5 Cd 0.5 S and semiconductor CaTiO3 first form S type heterostructure, not only accelerate the directional movement and separation of photo-generated electrons and holes, but also maintain the strong oxidation-reduction ability of photo-generated charge carriers. In addition, on the basis of S type heterostructure, load Ni3C cocatalyst, Ni3C nano-particle cocatalyst as electron capture center can not only provide more active sites, but also further improve the separation efficiency of charge.

This invention discloses a high-frequency ultrasound method for processing large-volume tissues. The method includes the step of placing biological tissues under high-frequency ultrasound conditions for processing. In the high-frequency ultrasound processing, the ultrasound frequency is 1 MHz, the sound intensity is 0.6 W / cm², and the temperature is 4℃. This invention also includes a high-frequency ultrasound system for processing large-volume tissues, characterized in that the system comprises a sample container or sample carrying platform module, a signal generation module, a power amplification module, an ultrasound transducer module, a temperature control module, and a circulating fluid circuit module. The high-frequency ultrasound method of this invention can be applied to the overall staining, tissue clearing, and resin embedding of large-volume tissues to improve the efficiency of the processing solution penetrating deeper into the tissue, improve the uniformity of internal and external tissue processing, and enhance the applicability of this method to fluorescent samples, thus possessing greater scalability and application value.

The application discloses a kind of liquid phase reduction silver powder wastewater resource processing method, comprising the following steps: (1) using membrane filtration method to remove suspended solids in silver powder wastewater;(2) using ultrasonic method to irradiate the clear silver powder solution obtained in step (1), obtain the solution containing low molecular weight pollutants;(3) using wet oxidation method to treat the solution containing low molecular weight pollutants obtained in step (2), obtain low COD acidic solution;(4) in the low COD solution obtained in step (3), add lye until pH is 6.0-7.0, prepare sodium nitrate solution;(5) using heavy metal capture agent to purify the sodium nitrate solution obtained in step (4);(6) using evaporation crystallization method to treat the pure sodium nitrate solution obtained in step (5), obtain high-purity sodium nitrate and condensate;Solve the existing liquid phase reduction silver powder wastewater treatment method cannot recover nitrogen resource and process safety is poor.

An ultrasound apparatus includes: a display unit configured to display on an ultrasound image a measuring device image including a plurality of measuring points which indicate points on the ultrasound image that are to be measured, and an adjusting portion for adjusting the plurality of measuring points; an input unit configured to receive a touch input for changing a position of the adjusting portion; and a controller configured to adjust a position of at least one of the plurality of measuring points based on the changed position of the adjusting portion, and to obtain a measurement value based on positions of the plurality of measuring points including the at least one measuring point, the position of which is adjusted, wherein the plurality of measuring points are disposed apart from the adjusting portion.

The application discloses a kind of titanium steel composite plate stress monitoring method and system based on wireless communication, and the application relates to stress monitoring technical field, lack of tool adaptation to multiple method cooperation is solved, leading to the technical problem of large stress monitoring error, low reliability, the application is by constructing hierarchical pretreatment-strain gauge pasting calibration-environment compensation-stress correction-internal ultrasonic cooperative monitoring complete system, cover outer / inside, multidirectional / interface stress monitoring, realize from environmental interference elimination to complex stress accurate calculation whole process control, improve stress monitoring precision, ultrasonic method is combined with titanium steel hierarchical acoustoelastic calibration, interface characteristics, accurately determine internal stress distribution;Through abnormal monitoring point density analysis, intelligently identify stress abnormal area, solve the problem that traditional method cannot accurately locate internal stress hidden danger, provide reliable data support for titanium steel composite plate safety evaluation, prevent structural failure caused by stress concentration.

Systems, devices, and methods for sparse synthetic aperture ultrasound (SSAU) imaging and / or range-Doppler applications are described. An example method for SAU imaging includes receiving, via a user interface, an input including an array topology comprising a particular N-dimensional arrangement of a plurality of transducer elements of the SAU system, an objective space, a function characterizing an imaging capability of the SAU system, and one or more constraints, generating, based on the input, an acoustic field over the objective space for each of the plurality of transducer elements of the array topology, selecting one or more transducer elements from the plurality of transducer elements of the array topology based on evaluation of the function, and providing for display, on the user interface, the selected one or more transducer elements that satisfy each of the one or more constraints.

The invention relates to the technical field of steel and iron material defect detection, and discloses a method for detecting large-size inclusions through axial force high-frequency fatigue, and the method comprises the following steps: preparing a steel sample in a specific shape, and controlling the hardness of the steel sample in a range of 30-50 HRC; an axial force high-frequency fatigue testing machine is used for carrying out a fatigue test under the parameters that the maximum stress is 60%-80% of the tensile strength of the material, the stress ratio is 0.1-0.5 and the frequency is 50-90 Hz, so that the sample is fractured from the weakest part in the sample; fractures, located inside, of the fracture source are screened, the three-dimensional morphology of the large-size inclusions at the fracture source is observed through a microscope, the size of the large-size inclusions is accurately measured, and component analysis can be conducted through an energy disperse spectroscopy. The method overcomes the defects that a traditional metallographic method is poor in statistical representativeness and an ultrasonic method cannot achieve visual observation, can directly and accurately detect the large-size inclusions with the largest harm in the steel, and has important value for evaluating the material purity and predicting the fatigue life.

This invention provides a transcranial ultrasound method and system for penetrating the skull. The method includes applying a decalcifying agent to the skull region of a subject to make the skull region acoustically transparent, thereby enabling brain imaging and / or brain therapy; transmitting and receiving sound wave signals to the acoustically transparent head using an ultrasound transducer; acquiring ultrasound images of internal tissues of the head based on the received sound wave signals; and / or transmitting ultrasound waves to the acoustically transparent head using the ultrasound transducer to perform ultrasound therapy. This transcranial ultrasound method fundamentally eliminates the strong reflection, scattering, and energy attenuation of ultrasound waves caused by the skull as an acoustic barrier, significantly improving signal strength. Therefore, this invention not only achieves non-invasive, whole-brain-depth functional ultrasound imaging with resolution up to 20 micrometers, but also greatly improves the accuracy and safety of ultrasound therapy procedures such as targeted drug delivery and neuromodulation.