The invention relates to a throat drug application device, in particular to a handheld throat drug application device, and aims at providing the handheld throat drug application device which is capable of adjusting the drug spraying amount and the drug spraying angle and replacing a spray nozzle. According to the technical scheme, the handheld throat drug application device includes a mounting rack, an arc block, a swing bar, a hard water pipe, a spray nozzle, a first return spring, a cover plate, a convex block, a flexible pipe, a first one-way valve, a fixing plate, a water containing bag and the like; the mounting rack is placed at the top of a frame, the arc block is arranged at the middle of the top of the interior of the mounting rack, the swing bar is rotatably arranged at the frontside of the arc block, and the hard water pipe is connected to the left end of the swing bar and is located at the front side of the mounting rack. According to the handheld throat drug application device, by arranging the swing bar, the spray nozzle can swing up and down, and therefore people can spray drug to the throat in all directions; by arranging the convex block, the spray nozzle can be fixed and can be replaced, and bacterial infection is avoided; by arranging a plug, people can adjust the drug spraying amount of the spray nozzle.