The invention belongs to the field of furniture manufacturing, and particularly relates to a panel machining and positioning device for furniture manufacturing. For the problems that manual positioning is needed during existing wood cutting, the machining efficiency is low, and the machining stability is poor, the following scheme is provided at present, the panel machining and positioning devicecomprises a bottom plate and at least one conveying clamping mechanism located on the bottom plate; supporting frames are arranged on the two sides of the bottom end of each conveying clamping mechanism, the bottom ends of the supporting frames are fixed to the bottom plate, and a plurality of auxiliary fixing mechanisms are arranged on the two side walls of each conveying clamping mechanism; twofixing columns are welded to the side wall of one conveying clamping mechanism, wherein a limiting plate is rotationally connected to one ends of the fixing columns, a second telescopic rod is hingedto the bottom end of the conveying clamping mechanism, and an output shaft of the second telescopic rod is hinged to the side wall of the limiting plate. By means of the panel machining and positioning device, panel conveying, positioning and fixing can be achieved, subsequent machining is convenient, the machining stability is high, automatic positioning can be achieved, and the panel machining efficiency is improved.