31results about How to "High degree of sensitivity" patented technology

A gene detection field-effect device provided with an insulation film (2), a semiconductor substrate (3), and a reference electrode (4), includes:(a) the insulation film (2) including a nucleic acid probe (5) immobilized on one of the surfaces thereof and is in contact with a sample solution (6) containing at least one type of a target gene (601) for detection and analysis; (b) the semiconductor substrate (3) being installed so as to abut against the other surface of the insulation film (2); and (c) the reference electrode (4) being provided in the sample solution (6).

A radiation monitoring system for detecting levels of radiation emitted from moving objects traveling at a wide range of speeds, including the high speeds normally encountered with vehicles traveling on highways, interstates, thoroughfares, railroads and conveyors. At least two and preferably three ionizing radiation detectors are employed, spaced apart in series along the direction of travel of the moving object or vehicle. The object or vehicle is monitored for radioactivity and the results are transmitted and processed at a central location. The individual results from each detector for a particular object or vehicle are summed and averaged over the number of detectors used thereby clearly distinguishing the fluctuating background radiation detected at each detector from the consistent high levels of radiation detected from those moving objects or vehicles measured emitting radiation. The results are cooperatively linked by an identification system such as a web cam or other photographic device which obtains visual identification of the objects and vehicles emitting the abnormally high levels of radiation detected.

Induced movement in a patient is detected and correlated with a TMS stimulating pulse so as to determine the patient's motor threshold stimulation level. Direct visual or audible feedback is provided to the operator indicating that a valid stimulation has occurred so that the operator may adjust the stimulation accordingly. A search algorithm may be used to direct a convergence to the motor threshold stimulation level with or without operator intervention. A motion detector is used or, alternatively, the motion detector is replaced with a direct motor evoked potential (MEP) measurement device that measures induced neurological voltage and correlates the measured neurological change to the TMS stimulus. Other signals indicative of motor threshold may be detected and correlated to the TMS stimulus pulses. For example, left / right asymmetry changes in a narrow subset of EEG leads placed on the forehead of the patient or fast autonomic responses, such as skin conductivity, modulation of respiration, reflex responses, and the like, may be detected. The appropriate stimulation level for TMS studies are also determined using techniques other than motor cortex motor threshold methods. For example, a localized ultrasound probe may be used to determine the depth of cortical tissue at the treatment site. When considered along with neuronal excitability, the stimulation level for treatment may be determined. Alternatively, a localized impedance probe or coil and detection circuit whose Q factor changes with tissue loading may be used to detect cortical depth.

A radio-frequency communication device arranged to transmit a transmitted signal from a transmitter antenna device toward a communication object, and to receive through a receiver antenna device a reply signal transmitted from the communication object, for radio communication with the communication object, the radio-frequency communication device including a transfer-function calculating portion operable to calculate a transfer function indicative of a relationship between a signal input to the transmitter antenna device and a signal generated by the receiver antenna device due to the signal input to the transmitter antenna device, and a receiver-circuit-constant setting portion operable to set a receiver-circuit constant for improving a quality of the reply signal received by the receiver antenna device, on the basis of the transfer function calculated by the transfer-function calculating portion, and the signal input to the transmitter antenna device.

Among others, the present invention provides apparatus for detecting a disease, comprising a system delivery biological subject and a probing and detecting device, wherein the probing and detecting device includes a first micro-device and a first substrate supporting the first micro-device, the first micro-device contacts a biologic material to be detected and is capable of measuring at the microscopic level an electric, magnetic, electromagnetic, thermal, optical, acoustical, biological, chemical, physical, or mechanical property of the biologic material.

Method for measuring gaseous emissions and / or flux based on using a spectrometer instrument for receiving absorption spectra to detect and record, in a wavelength-resolved manner, the electromagnetic radiation which is coming directly from the sun. The instrument is arranged in such a way that the connecting line between the instrument and the sun transects a gas volume which constitutes all or part of the gas flow emitted from a source. The electromagnetic radiation which is recorded is used for calculating the gas concentration along the optical connecting line in the gas volume. The concentration which is obtained in this way, and which is integrated over the cross-sectional area traversed by the connecting line, is used, together with information on the speeds of the wind, the instrument and the gas-emitting source, to calculate the gas flow through the cross-sectional area which is traversed.

Among others, the present invention provides apparatus for detecting circulating tumor cells, comprising a system delivery biological subject and a probing and detecting device, wherein the probing and detecting device includes a first micro-device and a first substrate supporting the first micro-device, the first micro-device contacts a biologic material to be detected and is capable of measuring at the microscopic level an electrical, magnetic, electromagnetic, thermal, optical, acoustical, biological, chemical, electro-mechanical, electro-chemical, electro-optical, electro-thermal, electro-chemical-mechanical, bio-chemical, bio-mechanical, bio-optical, bio-thermal, bio-physical, bio-electro-mechanical, bio-electro-chemical, bio-electro-optical, bio-electro-thermal, bio-mechanical-optical, bio-mechanical thermal, bio-thermal-optical, bio-electro-chemical-optical, bio-electro-mechanical-optical, bio-electro-thermal-optical, bio-electro-chemical-mechanical, physical or mechanical property, or a combination thereof, of the biologic subject.

Among others, the present invention provides micro-devices for detecting or treating a disease, each comprising a first micro sensor for detecting a property of the biological sample at the microscopic level, and an interior wall defining a channel, wherein the micro sensor is located in the interior wall of the micro-device and detects the property of the biological sample in the microscopic level, and the biological sample is transported within the channel.

Among others, the present invention provides apparatus for detecting circulating tumor cells, comprising a system delivery biological subject and a probing and detecting device, wherein the probing and detecting device includes a first micro-device and a first substrate supporting the first micro-device, the first micro-device contacts a biologic material to be detected and is capable of measuring at the microscopic level an electrical, magnetic, electromagnetic, thermal, optical, acoustical, biological, chemical, electro-mechanical, electro-chemical, electro-optical, electro-thermal, electro-chemical-mechanical, bio-chemical, bio-mechanical, bio-optical, bio-thermal, bio-physical, bio-electro-mechanical, bio-electro chemical, bio-electro-optical, bio-electro-thermal, bio-mechanical-optical, bio-mechanical thermal, bio-thermal-optical, bio-electro-chemical-optical, bio-electro-mechanical-optical, bio electro-thermal-optical, bio-electro-chemical-mechanical, physical or mechanical property, or a combination thereof, of the biologic subject.

The present invention provides, among others, apparatus for detecting a disease, comprising a system delivery biological subject and a probing and detecting device, wherein the probing and detecting device includes a first micro-device and a first substrate supporting the first micro-device, the first micro-device contacts a biologic material to be detected and is capable of measuring at the microscopic level an electric, magnetic, electromagnetic, thermal, optical, acoustical, biological, chemical, physical, or mechanical property of the biologic material.

A monitoring sensor for a sealed secondary battery 1 including a sealed outer casing 21 and an electrode group 22 including a polymer matrix layer 3 that is disposed in the inside accommodated in the inside of the sealed outer casing 21, of the outer casing 21 and a detection unit 4 that is disposed on the outside of the outer casing 21, wherein the polymer matrix layer 3 contains a filler that is dispersed therein and that changes an external field in accordance with deformation of the polymer matrix layer 3, and the detection unit 4 detects change in the external field.

A method and kit is described for individualized stool surveillance for occurrence / recurrence of preneoplastic or neoplastic lesions based on the analysis of genetic mutations and methylation pattern detected in biopsy tissue removed during polypectomie as compared to normal colon mucosa.

The invention relates to a flow sensor having a measuring chamber to which a fluid whose volume and / or rate of flow is to be measured is supplied and then drawn off. Inside the measuring chamber elements of a measuring mechanism are mounted so as to freely rotate. The sensor is also provided with a magnet which produces a magnetic field inside the measuring chamber and in close proximity thereto. At least one sensor device measures the magnetic field and / or changes in the magnetic field. The sensor device for measuring the magnetic field is provided with at least one giant magnetoresistance sensor.

Among others, the present invention provides apparatus for detecting a disease, comprising a system delivery biological subject and a probing and detecting device, wherein the probing and detecting device includes a first micro-device and a first substrate supporting the first micro-device, the first micro-device contacts a biologic material to be detected and is capable of measuring at the microscopic level an electric, magnetic, electromagnetic, thermal, optical, acoustical, biological, chemical, physical, or mechanical property of the biologic material.

An optical scanning system is described, including a rotor that is set up to rotate about an axis of rotation during a scanning process, an optical lens that is situated on the rotor in such a way that the lens is situated on the axis of rotation, an optical transmit unit that is situated on the rotor and is set up to send out a scanning beam in the direction of an optical axis of the lens, and an optical receive unit that is situated on the rotor and includes a detector that is set up to receive a reflected scanning beam, the detector being situated such that the reflected scanning beam is focused onto the detector by the lens.

A process for measuring total microbiological content in an aqueous medium includes adding a fluorescent dye to the aqueous medium, measuring the fluorescent signal in the aqueous medium to obtain a baseline fluorescent signal, releasing intracellular content of the microbiological matter into the aqueous medium by lysing the microbiological matter, measuring the fluorescent signal in the aqueous medium with the released intracellular content of the microbiological matter to obtain a second fluorescent signal, subtracting the baseline signal from the second fluorescent signal to obtain a net fluorescent signal and equating the net fluorescent signal with a microbiological content. Methods for measuring biofilm and adjusting for background noise are also provided.

The present invention provides an electrolyte measuring device that makes it possible to detect failure in the device with a high degree of accuracy. The electrolyte measuring device has: an ion-selective electrode to which an ion solution including ions is supplied; a reference electrode; a measurement section to measure a potential difference between the ion-selective electrode and the reference electrode; and a current measurement section to measure an electric current flowing in the reference electrode.

In a deformation detection method for a sealed-type rechargeable battery 1 in which an electrode group 22, which is formed by stacking a positive electrode 23 and a negative electrode 24 with a separator 25 interposed therebetween, is accommodated in a sealed outer casing 21, a polymer matrix layer 3 is attached to an outer surface of a wall portion 28a of the outer casing 21 that faces the electrode group 22 in a thickness direction of the positive electrode 23 and the negative electrode 24 or in a direction perpendicular to the thickness direction. The polymer matrix layer 3 contains a filler that is dispersed therein and that changes an external field in response to deformation of the polymer matrix layer 3. Change in the external field accompanying the deformation of the polymer matrix layer 3 is detected by a detection unit 4.

This monitoring sensor is provided with polymer matrix layers 3 containing a magnetic filler and attached to an outer casing or an electrode group, and a magnetism detection unit 4 for detecting a change in magnetism. The magnetic filler is magnetized in the in-plane direction of the polymer matrix layers 3. An interface layer 5 is formed between the polymer matrix layers 3 that are arranged with edges thereof facing each other. The directions of magnetization of the magnetic filler on one side and the other side having the interface layer 5 interposed therebetween are opposite to each other and intersect with the interface layer 5 as viewed in the thickness direction of the polymer matrix layers 3. The magnetism detection unit 4 is disposed on a straight line L1 passing through the interface layer 5 and extending in the thickness direction of the polymer matrix layers 3.

A method for determining the risk of an adverse pregnancy outcome for a woman is provided comprising the steps of measuring a level of TM7-H1 and optionally one or more of BVAB1, Sneathia amnii, and Prevotella cluster 2 in a vaginal sample obtained from the woman, and identifying the woman as having an increased risk for an adverse pregnancy outcome, or other adverse pregnancy outcomes, if the levels are increased compared to corresponding standard control levels. Methods for the prophylactic treatment of subjects identified as being at increased risk for an adverse pregnancy outcome are also provided.

The application is related to novel signature sequences for diagnosis of Mycobacterium tuberculosis in clinical samples with 100% specificity and a very high degree of sensitivity.

Measurement of expression levels of heat shock factor Y chromosome (HSFY) in testicular tissue samples or semen can be used to identify whether testicular sperm extraction can be used for patients with all histological variants of nonobstructive azoospermia.