The invention relates to a flexible sheetmetal processing center, belonging to sheetmetal processing equipment. The flexible sheetmetal processing center mainly comprises a motor and a servo motor, a main spindle box, a main spindle assembly, a screw rod component, a pedestal, crossbeams, a back-blading device, an upright column, a tool storage, a clamping assembly, a linear guide rail assembly, an electric control box and a base, wherein the main spindle box is arranged on the linear guide rail of the upright column and moves up and down to realize a Z-direction coordinate motion; the upright column is arranged on the linear guide rail assembly of the base to realize a Y-direction coordinate motion; a universal rolling ball array is respectively arranged on a left support table and a right support table which are used for supporting sheetmetal parts needing to be processed; a left crossbeam assembly and a right crossbeam assembly can move in the longitudinal direction to form an X-direction coordinate motion; and through a W-direction motion of the back-blading part and a W-direction main spindle rotating motion, back-blading to burrs and chamfers can be automatically carried outon the bottom surface, therefore good manufacturability and high quality and efficiency of sheetmetal processing are achieved, and processing cost is reduced very remarkably. The flexible sheetmetal processing center disclosed by the invention is widely suitable for hole drilling, thread tapping, counter boring, burr back-blading at bottoms of holes, irregular hole milling and cutting and plate pattern etching and milling of the sheetmetal parts.