The invention relates to a preparation method of tubular porous
bacterial cellulose. According to the preparation method, double
layers of
oxygen-permeating materials are nested to form a hollow
oxygen-permeating mold for culturing
bacterial cellulose, an inner
pipe and an outer
pipe of the mold can shrink / relax along the radial direction in a periodical alternation manner by accurately adjusting the pressure and the
oxygen volume concentration of the
internal pressure gas of the inner
pipe and the external gas of the outer pipe of the hollow oxygen-permeating mold; and simultaneously sustained release microspheres which can release oxygen or a
sugar source slowly are added into a culture solution so as to prepare the tubular porous
bacterial cellulose. According to the preparation method, the effective area in the bacterial
cellulose is expanded by more than one time, the culture period is shortened, the outer wall of the tubular bacterial
cellulose is compact, the suturing performance of materials is improved, the probability of
intimal hyperplasia and
thrombus at the suturing position after the tubular porous bacterial
cellulose is planted into a
human body is lowered, and a formed porous structure is beneficial to the entering of cells and
nutrient substances into the materials; and the material preparation period is short, the preparation process is environment-friendly, simple and fast, and the preparation cost is low.