30results about How to "Modulate immune activity" patented technology

The invention relates to the field of protein, and in particular to a bioactive polypeptide SKHSSLDCVL, and a preparation method and application thereof. An amino acid sequence of the bioactive polypeptide SKHSSLDCVL is Ser-Lys-His-Ser-Ser-Leu-Asp-Cys-Val-Leu. An in-vitro antioxidant experiment and an in-vitro immunological function promoting experiment verify that the bioactive polypeptide SKHSSLDCVL has better antioxidant biological activity and a better immune modulating function; on one hand, the bioactive polypeptide SKHSSLDCVL has better antioxidant activity and is capable of removing free radicals in a body and increasing the quality of life; on the other hand, the bioactive polypeptide SKHSSLDCVL is capable of enhancing in-vitro proliferation ability of lymphocytes and macrophages, promoting the ability of swallowing neutral red by the macrophages, increasing the ability of defending external pathogen infection by the body and reducing the morbidity of the body, and has a very important significance in developing food, healthcare products and drugs having an immune modulating function and an antioxidant function.

The invention relates to the field of protein, in particular to a bioactive peptide SKVLPVPEKAVPYPQ as well as a preparation method and an application thereof. An amino acid sequence of the bioactive peptide SKVLPVPEKAVPYPQ is Ser-Lys-Val-Leu-Pro-Val-Pro-Glu-Lys-Ala-Val-Pro-Tyr-Pro-Gln. An in-vitro anti-oxidation experiment and an in-vitro immunity function promoting experiment prove that the bioactive peptide SKVLPVPEKAVPYPQ has better anti-oxidation biological activity and immunity regulation function, on one hand, the bioactive peptide SKVLPVPEKAVPYPQ has better anti-oxidation activity, can clear free radicals in an organism and improves life quality; on the other hand, by the aid of the bioactive peptide SKVLPVPEKAVPYPQ, in-vitro proliferation capacity of lymphocytes and macrophages can be enhanced, the phagocytosis capacity of the macrophages for neutral red is improved, the organism's capacity of resisting outside pathogen infection is improved, morbidity of the organism is reduced, and therefore, the bioactive peptide SKVLPVPEKAVPYPQ has quite great significance in development of food, healthcare products and drugs with an immune regulation function and an anti-oxidation function.

The invention relates to the field of protein, in particular to a bioactive polypeptide PMIGVNQELAY, and a preparation method and application thereof. The amino acid sequence of the bioactive polypeptide PMIGVNQELAY is Pro-Met-Ile-Gly-Val-Asn-Gln-Glu-Leu-Ala-Tyr. In vitro antioxidant experiments and in vitro immune function promoting experiments prove that the polypeptide PMIGVNQELAY has better antioxidant biological activity and immune modulating functions; on one hand, good antioxidant activity is realized; free radicals in the body can be cleared away; the life quality is improved; on the other hand, the bioactive polypeptide PMIGVNQELAY can enhance the in vitro multiplication capacity of lymphocytes and macrophages; the capability of the macrophages for devouring toluylene red is promoted; the capability of the body for resisting the external pathogen infection is improved; the body morbidity is reduced; very important significance is realized for developing food, health care products and medicines with the immune modulating function and the antioxidant function.

The invention relates to the field of protein, and in particular to a bioactive polypeptide TIASGEPT, and a preparation method and application thereof. An amino acid sequence of the bioactive polypeptide TIASGEPT is Thr-Ile-Ala-Ser-Gly-Glu-Pro-Thr. An in-vitro antioxidant experiment and an in-vitro immunological function promoting experiment verify that the bioactive polypeptide TIASGEPT has better antioxidant biological activity and a better immune modulating function; on one hand, the bioactive polypeptide TIASGEPT has better antioxidant activity and is capable of removing free radicals in a body and increasing the quality of life; on the other hand, the bioactive polypeptide TIASGEPT is capable of enhancing in-vitro proliferation ability of lymphocytes and macrophages, promoting the increment of nitric oxide induction amount of the macrophages, increasing the ability of defending external pathogen infection by the body and reducing the morbidity of the body, and has a very important significance in developing food, healthcare products and drugs, which have an immune modulating function and an antioxidant function.

The invention relates to the field of protein, in particular to a bioactive peptide DRAAHVKQVL as well as a preparation method and an application thereof. An amino acid sequence of the bioactive peptide DRAAHVKQVL is Asp-Arg-Ala-Ala-His-Vla-Lys-Gln-Val-Leu. An in-vitro anti-oxidation experiment and an in-vitro immunity function promoting experiment prove that the bioactive peptide DRAAHVKQVL has better anti-oxidation biological activity and immunity regulation function, on one hand, the bioactive peptide DRAAHVKQVL has better anti-oxidation activity, can clear free radicals in an organism and improves life quality; on the other hand, by the aid of the bioactive peptide DRAAHVKQVL, in-vitro proliferation capacity of lymphocytes and macrophages can be enhanced, the macrophages are promoted to secrete cytokines, the organism's capacity of resisting outside pathogen infection is improved, morbidity of the organism is reduced, and therefore, the bioactive peptide DRAAHVKQVL has quite great significance in development of food, healthcare products and drugs with an immune regulation function and an anti-oxidation function.

The invention relates to the field of proteins, in particular to bioactive polypeptide LVYPFPG as well as a preparation method and application thereof. An amino acid sequence of the bioactive polypeptide LVYPFPG is Leu-Val-Tyr-Pro-Phe-Pro-Gly. In-vitro antioxidant experiments and in-vitro immune function promotion experiments prove that the polypeptide LVYPFPG has better antioxidant biological activity and an immune regulation function; on the one hand, the polypeptide LVYPFPG has the better antioxidant activity, thus being capable of removing free radicals in a human body and further improving the quality of life; on the other hand, the bioactive polypeptide LVYPFPG can enhance the in vitro proliferative capacity of lymphocytes and macrophages and promote the neutral red phagocytosis of the macrophages, thus improving the external pathogen infection resistance of the organism and reducing the morbidity of the organism; therefore, the bioactive polypeptide LVYPFPG has a very important significance for developing food, health care products and medicines which have the immune regulation function and the antioxidant function.

The invention relates to the field of proteins and particularly relates to bioactive polypeptide ATLEDSPEVI as well as a preparation method and application thereof. The amino acid sequence of the bioactive polypeptide ATLEDSPEVI is Ala-Thr-Leu-Glu-Asp-Ser-Pro-Glu-Val-Ile. In-vitro anti-oxidation experiments and in-vitro immune function promotion experiments verify that the polypeptide ATLEDSPEVI has better antioxidant biological activity and immune modulating function, so that on one hand, the polypeptide ATLEDSPEVI has better antioxidant activity, so that free radicals in a body can be removed, and the quality of life is improved; on the other hand, the polypeptide ATLEDSPEVI can enhance the in-vitro multiplication capacity of lymphocytes and macrophages, the macrophages are promoted to secrete cytokines, the capability of the body in defense for external pathogen infection is enhanced, and the incidence rate of the body is reduced. Therefore, the polypeptide ATLEDSPEVI has great significance in development of food, health-care products and drugs with immune modulating function and antioxidant function.

The invention discloses probiotic powder with an anti-oxidation function and a preparation method thereof. The probiotic powder with the anti-oxidation function is prepared from lactobacillus kefir KL22 and lactobacillus plantarum N3117; and oligosaccharides, marine polysaccharides and maltodextrin are utilized as compound components so as to carry out processing and preparation. The prepared probiotic powder has very good hydroxyl free radical (HO.) scavenging capability, superoxide anion free radical (O2-.) scavenging capability and 1,1-diphenyl-picryl hydrazinyl free radical scavenging capability.

The invention relates to the field of proteins, in particular to a bioactive polypeptide EINTVQVTST and a preparation method and application thereof. An amino acid sequence of the bioactive polypeptide EINTVQVTST is Glu-Ile-Asn-Thr-Val-Gln-Val-Thr-Ser-Thr. By virtue of in-vitro antioxidant experiment and in-vitro immunity promoting experiment, the polypeptide EINTVQVTST is proved to have good antioxidant bioactivity and immunity regulation function, has good antioxidant activity on one hand, and can eliminate free radicals in the body and improve the quality of life; and on the other hand, the bioactive polypeptide EINTVQVTST can improve the in-vitro proliferation capacity of lymphocyte and macrophage, promotes the macrophage to secrete cell factors, improves the capacity of the body for resisting external pathogenic infection, decreases the disease rate of the body, and has important significance for developing food, healthcare products and drugs with an immunity regulation function and an antioxidant function.

The invention discloses a traditional Chinese medicine composition for benefiting qi, nourishing blood, maintaining beauty and keeping young and a preparation method and application of the traditionalChinese medicine composition. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 125-145 parts of chicken fetuses, 1-10 parts of radix astragali, 1-10 parts of radix glycyrrhizae, 1-10 parts of ginseng and 2-10 parts of flos lonicerae. All the components are matched with one another, the remarkable effects of tonifying qi, nourishing blood, maintaining beauty, keeping young and improving sleep are achieved, all the medicinal materials are medicinal and edible traditional Chinese medicinal materials or traditional Chinese medicinal materials capable of being used for health-care food, long-term medication experience is achieved, and toxic and side effects are avoided.

The invention discloses a natural nutrient regulator for aquaculture. The nutrient regulator comprises the following components in parts by weight: 2-5 parts of astragalus membranaceus, 3-8 parts of liquorice, 1-3 parts of nano-selenium, 2-6 parts of nano-zinc oxide, 2-5 parts of bacillus, 5-10 parts of protease, 5-10 parts of glucoamylase, 2-10 parts of lactic acid bacteria and 10-20 parts of deionized water. The nutrient regulator for aquaculture disclosed by the invention is purely natural, non-toxic, and free of secondary pollution; the immunity of an aquatic product can be effectively improved; and nutrients required for health growth of the aquatic product can be provided.

The invention discloses a composition suitable for the recovery phase of a hyperlipidemia type acute pancreatitis patient and a preparation method thereof. The composition comprises the following components in parts by mass: 20 parts of polypeptide powder, 72 parts of carbohydrate and 8 parts of fat powder; and the composition further comprises micronutrients. According to the invention, the total nutrient intervention in the recovery phase of the hyperlipidemia type acute pancreatitis can be carried out starting from the synthesis route of triglyceride in liver and adipose tissues, the blood fat level in the body is reduced, the promotion effect of blood fat on the disease course is reduced, meanwhile, the effects of resisting inflammation, resisting oxidation and adjusting immunocompetence are achieved, and disease relapse is inhibited. In addition, corresponding nutrients are supplemented according to the high metabolism state of the patient in the acute phase, and sufficient nutrition is provided for the patient.

The invention provides an immunity reinforcing agent for aquatic animals. The immunity reinforcing agent is characterized by comprising the following components in parts by mass of 17-28 parts of dandelions, 19-25 parts of radix astragali, 1-25 parts of licorice roots, 2-5 parts of bacillus, 5-18 parts of protease, 13-20 parts of silybum marianum, 2-3 parts of garlic, 1-2 parts of fresh ginger, 7-8 parts of heartleaf houttuynia herbs and 13-28 parts of spirulina, and also comprises 8-12 parts of giant knotweed rhizomes and 5-15 parts of haws. The immunity reinforcing agent disclosed by the invention has the characteristics of being capable of treating both manifestation and root cause of diseases, safe, low in toxicity, pollution-free, free from residues and the like, and concurrently hasthe efficacy of restraining bacteria, resisting bacteria, being capable of enhancing immunity of aquatic animals, resisting bacteria, preventing and treating parasite, resisting viruses, promoting growth of the aquatic animals and the like, and production of drug tolerance is not liable to cause; and the immunity reinforcing agent is suitable for aquatic animals at each growth stage, can regulatemicrobial population balance of intestinal tracts of the aquatic animals, through nutrition competition, attachment site competition or secretion of toxins of antibiotics, bacteriocin and the like, pathogenic microorganisms are killed or restrained, the anti-infection capacity is strengthened, the immunocompetence of intestinal mucosa of organisms is regulated, and the survival rate of animals during suffering from disease attack is increased.

The invention belongs to the field of health foods, and discloses wheat seedling noodles with the detoxifying and beautifying functions. The noodles are prepared from the following components in partsby weight: 80-90 parts of wheat flour, 25-45 parts of wheat seedling juice, 5-10 parts of aloe pulp, 35-45 parts of kudzuvine root powder, 1-3 parts of dietary alkali, 1-3 parts of table salt, 1-5 parts of vitamin E and 1-2 parts of sodium citrate. According to the noodles, the wheat seedling juice, the aloe pulp and the kudzuvine root powder are compounded, the synergistic effect among the nutrient substances and the functional components of the wheat seedling juice, the aloe pulp and the kudzuvine root powder is utilized, so that the blood vessel state is improved, harmful substances such as waste and impurities in vivo are removed, damaged cells of a human body can be helped to be repaired, meanwhile, the cell immunity is enhanced, sufficient nutritional ingredients are supplemented for the human body, and therefore the human body can be quickly restored to a healthy state, and the detoxifying and beautifying purposes are achieved.