The invention discloses a blood vessel dredging and cleaning device. The device comprises a balloon catheter, a balloon and a marking ring, wherein the balloon is wrapped at a distal end of the balloon catheter, a distal end and a proximal end of the balloon are respectively fixedly connected with the balloon catheter passing through the balloon, the marking ring is arranged at the distal end anda proximal end of the balloon catheter, a balloon expansion channel and a guide wire guide channel are arranged in the balloon catheter, a communication hole is formed in a wall of the balloon catheter, an overall shape of the balloon in the inflated state is a truncated cone or a cone, the distal end of the balloon is a large diameter end, and the proximal end is a small diameter end, the balloonis composed of a distal end surface, a proximal end surface, a tapered side wall, and a unit plug-removing protrusion, the distal end face is in arc transition connection with the conical side wall,the proximal end face is in arc transition connection with the conical side wall, the unit thrombus removal protrusions are distributed on the conical side wall of the balloon at intervals, and the unit thrombus removal protrusions are provided with protrusion cavities. The device has advantages of novel structure, good thrombus removal effect, little damage to blood vessel wall and the like.