The invention discloses a special LED lighting device for animal experiments, which comprises an LED lighting system, an animal hair and dust collection system and an intelligent control system, wherein the animal hair and dust collection system is connected with the LED lighting system; the intelligent control system is connected with the LED lighting system and the animal hair and dust collection system respectively; the animal hair and dust collection system comprises a motor, wind wheels, an upper cover, a wind scooper, an air filter element, a lower cover, an air filter element fixing screw rod, upper cover wind outlets and HEPA filter bags; animal hairs and large-particle dust in air are filtered and collected by the air filter element, and small-particle dust in air is filtered and collected by the HEPA filter bags. The special LED lighting device is reasonable in design and simple to maintain, can provide a lighting system with high efficiency, low energy, uniform illumination and good light quality for animal experiments, and meanwhile, can effectively clean air, improve the working environment, remarkably improve the stability and prolong the service lives of instruments and equipment.