61 results about "Lung tuberculosis" patented technology

Methods and systems are disclosed for the detecting of whether a subject has a lung disorder such as asthma, tuberculosis or lung cancer. Monitoring the subject's health and prognosis is also disclosed.

The invention provides a full-nutritional formulated food, a specific full-nutritional formulated food or a non-full-nutritional formulated food, which is used for being eaten by patients with tuberculosis. According to the requirements of General Rule of Formulated Food for Special Medical Purposes, on the basis of the quintessential theories such as 'harmony of removing and reinforcing' and 'balanced nursing' of traditional Chinese medicines (simultaneously regulating liver, spleen and kidney is taken as a main principle), and in combination with the physical characteristics of patients with tuberculosis, a formula is developed through integrating advanced research achievements in physiology, medicine, nutriology, clinical applications and the like at Harvard University in America today. The full-nutritional formulated food is prepared by taking more than ten medicinal-edible traditional Chinese medicine extract essences, various probiotics and prebiotics as main raw materials and taking short peptides, an amino acid, water soluble dietary fibers, compound vitamins and composite mineral substances as auxiliary materials, so that the full-nutritional formulated food not only can be used as a single nutrient source for meeting the nutritional needs of patients with tuberculosis, but also achieves the effects of strengthening spleen and tonifying lung, clearing away heat and toxic materials, tonifying middle-Jiao and Qi, preventing phlegm from forming and stopping coughing, tonifying lung and clearing heat, and preventing and treating tuberculosis.

The invention discloses a protein B12 expression inhibitor and an application thereof in immunization and treatment of TB (tuberculosis). B12 can mediate the immune process of TB and may weaken immunememory of TB infection through CD272 to cause immune tolerance of MTB (mycobacterium tuberculosis). Therefore, a substance for inhibiting expression of B12 protein, a substance for reducing activityof the protein B12 or inactivating the protein B12, or a substance for promoting degradation of the protein B12 is expected to be prepared to enhance immunity of a patient with TB and achieve the TB treating effect. Besides, studies show that miR-16 can target B12, and a lentivirus containing the gene miR-16 can reduce expression of B12 in T lymphocytes of the patient with TB, so, miR-16 can be applied to preparation of the protein B12 expression inhibitor.

The invention discloses a CT image-based interpretable pulmonary tuberculosis classification network identification method, comprising the following steps: acquiring a CT image of a person to be tested for lung computed tomography, normalizing and scaling the lung parenchyma image; establishing and training Interpretable pulmonary tuberculosis classification network, interpretable pulmonary tuberculosis classification network is built on the basis of residual network and adding Dense idea and improved attention mechanism; normalized and scaled to 512x512 size lung parenchyma image is sent into To the trained interpretable tuberculosis classification network, the classification results of tuberculosis of the test person and the corresponding class activation heat map are obtained and output in the host computer. According to the invention, the classification result of pulmonary tuberculosis of the person to be tested can be obtained and the corresponding class activation heat map can be output according to the CT image of the person to be tested.

This application relates to the field of biomedical technology, in particular to miRNA markers related to active tuberculosis and their applications, wherein the miRNA markers related to active tuberculosis include miR-451a, miR-25-3p, miR-425 ‑5p, miR‑1260b, miR‑1273g‑3p, miR‑30e‑5p, miR‑140‑3p, let‑7a‑5p, miR‑1290, miR‑491‑5p, miR‑3615, miR‑15a‑5p One or more of miR-21-3p, miR-424-5p, miR-1268a, miR-1301-3p, miR-345-5p, miR-572, miR-375, miR-151a-5p.