The invention relates to an in-vitro simulated
dissolution and continuous online detection device for
nicotine in bagged
oral tobacco products. The device comprises a color developing agent containing device (R1), a
dissolution agent containing device (R2), a first
peristaltic pump (P1), a second
peristaltic pump (P2), a
dissolution pool (A), a decolorizing column (B), a reaction
pool (R) and a spectrophotometer (D), wherein the first
peristaltic pump (P1) is positioned at the downstream of the color developing agent containing device (R1) and is connected with the color developing agent containing device (R1) by virtue of a pipeline; the second peristaltic pump (P2), the dissolution
pool (A), the decolorizing column (B), the reaction pool (R) and the spectrophotometer (D) are positioned at the downstream of the dissolution agent containing device (R2) and are sequentially connected with one another; the reaction pool (R) is positioned at the downstream of the first peristaltic pump (P1) and is connected with the first peristaltic pump (P1) by virtue of a pipeline; and the spectrophotometer (D) is connected with a
data processing device (C). The invention also relates to an in-vitro simulated dissolution and continuous online detection method for the
nicotine in the bagged
oral tobacco products. According to the detection device and method disclosed by the invention, the continuous on-line detection of in-vitro dissolution for the
nicotine can be realized, the operation is convenient, and the detection is rapid.