The invention discloses a can body seal detection device. The device structurally comprises a lifting adjusting disc, a lifting rod, a secondary seal device, a conveying way, a driver, a control electric box, a control panel, an alarm device, a seal detection instrument, a seal cover shell, a power starting device, a gear transmission mechanism, a lever transmission mechanism, an air pressure sealmechanism, an auxiliary fixing mechanism, a fixing stabilizing mechanism and a balance buffer mechanism. According to the can body seal detection device, when the device detects a non-seal product, acan body can be fixed and stabilized automatically, secondary seal is carried out, manual treatment by a worker is not needed, the device is easy and convenient, labor force of a worker is effectively saved, the inner structure is stable, the device is more intelligent, and product production efficiency is greatly improved.