The invention provides a vortex street type cloud and mist air purification device. The vortex street type cloud and mist air purification device comprises a fan, a hollow cylinder, a cloud and mist generator suite, a cloud and mist mixing section, a rectification damping net, an electrode plate, a high-voltage electrode plate, a grounding electrode plate, an electrode plate and the like. By utilizing flow field characteristics of vortex and turbulent flow in cylindrical streaming wake flow and a charged cloud and mist trapping technology, automatic suction of cloud and mist, interaction of charged cloud and mist and fine particles in dust-containing airflow, Brownian motion, suction of coulombic force and coalescence of fine particles and cloud and mist caused by vortex and turbulent flow are realized, and under the coupling action of multiple coalescence forms, liquid drops with relatively large particles are quickly formed and are deposited and recycled under the action of electrostatic force. The PM2.5 removal efficiency is high, the energy consumption is low, the water consumption is low, the structure is compact, and an existing ventilation system can be conveniently transformed.