60results about How to "Preparation applicable" patented technology

The invention belongs to the technical field of medicines, and discloses a delivery system based on protein-phospholipid. The system comprises a protein-phospholipid dispersion with the weight ratio of between 1:100 and 100:1, wherein the grain size of the protein-phospholipid is between 5 and 1,000nm, and the surface of the phospholipid or the surface and the inside of the phospholipid are coated / covered by a protein layer. The preparation method comprises: preparing a phospholipid containing phase, preparing a protein containing water phase, performing the homogenization treatment on the phospholipid containing phase and the protein containing water phase at a temperature of between 0 and 40 DEG C and under a pressure of between 400 and 40,000psi, and obtaining a dispersion system with the average grain size of less than 1,000nm. The delivery system has the advantages of realizing the delivery in various ways such as injection, oral taking, cavities and canals, skin and the like, and lowering side effects of medicines. The delivery system solves the problems of drug-loading rate and stability of protein nano-grain and liposome, and adopts low-toxicity organic solvent, even no organic solvent; and the preparation method is easy for industrialized application, and can prepare a liquid type protein-phospholipid containing delivery system.

The invention relates to a degradable synthetic polymer and natural extracellular matrix composite material, an artificial blood vessel and a preparation method thereof. Degradable synthetic polymer components during preparation can be selected from one or more materials to perform proportioning; support materials with different fiber diameters, different fiber arrangement, different apertures anddifferent pore structures can be prepared through various technologies such as electrospinning, wet spinning, melt spinning, 3D printing, pouring, phase separation and particle leaching; and naturalextracellular matrix components are wide in sources, can be selected from vascular tissues (such as the arteries and veins of pigs and cows) of different species of animal sources or the vascular tissues (such as umbilical cords) of human donors, and can flexibly adjust the components and content thereof according to needs. The composite material and the artificial blood vessel prepared by the preparation technology can have good mechanical properties, controllable space structures, appropriate degradation velocity and excellent biocompatibility and biological induction activity; and the composite material, the artificial blood vessel and the preparation method are simple in preparation technology, high in controllability, mild in condition and suitable for large-scale industrial production.

The invention provides a TiO2 / PI hybridization film with photocatalysis and self-cleaning function and the process for preparing it, which is characterized in that adding organic monomer in the process of preparing thin films with sol-gel processing, with titanium collosol hydrolytic polymerization happening, forming medlin phase (PAA) in original position polyreaction, finally, forming a nanometer crystal phase TiO2 / PI hybridization film after heat treating. The thickness of hybridization film is not less than 300nm, which higher than anatase nanometer crystal phase obtained from common puretitanium collosol. There isn't crackle and flake for film in the process of heat treating. Chosing a suitable medlin leading body, a Ti-S bond is formed at the same time of forming a hydrogen bond inthe hybridization film, which endowing film with photocatalysis and self-cleansing effect under the visible light. And the photocatalysis and self-cleansing effect of the film are higher than the photocatalysis activity of common titanium oxide nanometer crystal phase film, meanwhile, the film has good radiation resistant and chemical stability.

The invention discloses a method for preparing a large-scale flake-like ultra-high thermal conductivity diamond / copper composite material, relating to a method for preparing a diamond / copper composite material. The purpose is to solve the problems of low thermal conductivity and poor interfacial bonding strength of diamond / copper composites. Method: Fill the diamond particles coated with metal film into the cavity of the graphite mold to obtain the preform; the preform is placed in the crucible, and the block pure copper and copper alloy are placed on the upper part of the preform in the crucible, and placed in the air pressure In the impregnation furnace, under the protective atmosphere of argon, the microstructure and morphology of the interface layer material are controlled, the temperature is raised to melt copper, heat preservation and pressure-holding infiltration, and finally pressure-holding stepwise cooling. The diamond volume fraction in the obtained composite material member is 60%-85%, the thermal conductivity reaches 1500W / mK, the side length reaches 60-130mm, and the thickness reaches 0.2-4mm. The invention is suitable for preparing diamond / copper composite material with high thermal conductivity.