30 results about "Creatine Monohydrate" patented technology

According to the creatine-monohydrate pectin soft sweets and the preparation method, the low-amidation pectin is innovatively used in the field of the creatine-monohydrate pectin soft sweets through corresponding pretreatment, so that the problems caused by reaction and decomposition of an amphoteric compound, namely creatine monohydrate, in an original high-ester pectin system are solved; meanwhile, the problem that conventional low-amidation pectin cannot be gelatinized during pouring is solved, the low-amidation pectin and the creatine monohydrate are innovatively combined, and a gel system capable of containing a high-concentration creatine monohydrate compound is prepared. And meanwhile, by adopting a sugar-free formula technology, the requirement that sports people need to supplement creatine monohydrate but do not wish to intake sugar is met.

This invention provides a continuous method for preparing high-purity creatine monohydrate, comprising the following steps: a) adding chloroacetic acid aqueous solution dropwise to an aqueous methylamine solution, stirring at room temperature for 2 hours after the addition is complete; b) heating to 50-60°C and holding for 1 hour to remove most of the methylamine, then heating to 95°C to evaporate the methylamine aqueous solution for 1 hour; c) adding sodium hydroxide solution dropwise to the solution from step b) at 95°C, then heating to 105°C and concentrating under reduced pressure for 1.5 hours to approximately half the original volume, obtaining a creatine solution with a concentration of 30%-40%; d) cooling the solution from step c) to 40-60°C and adding a catalyst; e) drying to obtain pure creatine monohydrate. This invention reduces the methylamine equivalent, saving costs, and eliminates the need for purifying creatine for direct use in the next reaction; it can simultaneously lower the system reaction temperature and pH value to inhibit the formation of byproducts dicyandiamide and creatinine, and eliminates the need for debittering agents for purification and debittering, thus saving production costs.

The invention provides a creatine monohydrate synthesis reaction device, and belongs to the technical field of creatine monohydrate production. Comprising a plate-and-frame filter, a filter frame is mounted in the middle of the plate-and-frame filter, and a speed brake is fixedly connected to the bottom of the filter frame; the dip angle scraping assembly is used for being matched with a worker to scrape a filter cake on the filter frame, and the dip angle scraping assembly is connected with the portal frame. By arranging the dip angle scraping assembly, when filter cakes are scraped, a scraper on a speed brake can slowly scrape the filter cakes from bottom to top along a filter frame, and due to the fact that the scraper is designed in an inclined mode, the contact area between the scraper and the filter cakes is small, excessive filter cake residues attached to the scraper can be reduced, and the resistance for cutting into a viscous layer can be greatly reduced; therefore, the filter cake is scraped more easily, the scraping efficiency is improved, the forming capacity of the filter cake is improved, and effective judgment of the NIR moisture meter on the moisture content of the filter cake in the subsequent drying process is facilitated.

The application provides a creatine monohydrate synthesis reaction device and belongs to the technical field of creatine monohydrate production. The device comprises a plate-and-frame filter, a filter frame is installed at the middle position of the plate-and-frame filter, and a deceleration plate is fixedly connected to the bottom of the filter frame. An inclination scraping assembly is used to scrape the filter cake on the filter frame in cooperation with workers, and the inclination scraping assembly is connected with the portal frame. The inclination scraping assembly is provided, and when the filter cake scraping operation is performed, the scraper on the deceleration plate can slowly scrape from bottom to top along the filter frame. Since the scraper is designed to be inclined, the contact area with the filter cake is small, which can not only reduce the excessive filter cake residues adhered to the scraper, but also greatly reduce the resistance of cutting into the viscous layer, so that the filter cake can be scraped more easily, the scraping efficiency is improved, and the forming capacity of the filter cake is improved, which facilitates the effective determination of the NIR moisture meter on the filter cake moisture content in the subsequent drying process.

The invention discloses a biosynthesis process of creatine monohydrate, and belongs to the technical field of bioengineering. The invention discloses a creatine monohydrate biosynthesis method, which is characterized in that sarcosine invertase is utilized to catalyze chloroacetic acid and monomethylamine to generate N-alkylation reaction so as to prepare sarcosine, and then creatine monohydrate is generated under the catalysis of the creatine invertase, the process is mild in reaction condition, the temperature is 25-37 DEG C, the pH is 6.0-8.0, the energy consumption is lower, the conversion efficiency is high, the environment is protected, and the economical efficiency is high. The invention provides a new synthesis method for sustainable synthesis of creatine monohydrate, and provides a new idea for industrial production of creatine monohydrate.

The invention belongs to the technical field of nutritional supplements, and particularly relates to a novel nutritional composition and application thereof. Comprising creatine monohydrate and a Chinese wolfberry extract, and the weight ratio of the creatine monohydrate to the Chinese wolfberry extract is (0.5: 1)-(3: 1). Experiments find that after a human body takes the nutritional composition, the content of phosphocreatine PCr in muscles can be increased by 14%-19%, the 1-RM strength can be increased by 6.1%-8.5%, and it is indicated that the nutritional composition has the effect of improving the functional muscle strength and the phosphocreatine level. And the effect generated by the nutritional composition is far beyond the sum of the independent effects of all the components, so that the combination of the creatine monohydrate and the wolfberry extract has an unexpected and non-obvious synergistic effect in the aspects of improving the functional muscle strength and the creatine phosphate level.

The invention provides a method for analyzing a creatine monohydrate molecule hydrogen bond network and a vibration mode based on a terahertz spectrum. The method comprises the following steps: carrying out terahertz spectrum measurement on a creatine monohydrate sample at different temperatures (for example, the temperature is reduced from 300 K to 4.5 K) to obtain absorption spectrum data in a wave band of 1-14 THz; analyzing the spectral data, and dividing the absorption peaks according to a characteristic frequency of about 9.95 THz: defining the absorption peaks lower than the frequency as a hydrogen bond network vibration region, and defining the absorption peaks higher than the frequency as an intramolecular vibration region; the crystal structure of creatine monohydrate and the stability of the hydrogen bond network are evaluated and identified by observing a blue shift phenomenon of an absorption peak of a vibration area of the hydrogen bond network along with temperature reduction and local vibration characteristic peaks appearing at 6.58 THz and 7.97 THz at a specific temperature (such as lower than 200K). According to the method, a technical means for directly and nondestructively representing the dynamic characteristics of the creatine monohydrate crystal lattice is provided by establishing the corresponding relation among the temperature, the frequency and the vibration mode.

The invention relates to the technical field of creatine monohydrate production, in particular to a creatine monohydrate conveying and feeding device for creatine monohydrate food processing.The creatine monohydrate conveying and feeding device comprises a bearing base and a feeding assembly, and the feeding assembly comprises a height adjusting piece, a connecting base, a feeding hopper, a material guiding frame, a screening piece, two spiral feeding rods, two transmission shafts and a driving mechanism; a creatine monohydrate raw material is put into the feeding hopper, then impurity screening is conducted on the creatine monohydrate raw material through the screening piece, the creatine monohydrate raw material is dispersed in the screening process and then falls into the feeding hopper, the driving mechanism is controlled to drive the two transmission shafts to drive the two spiral feeding rods to rotate, and then the creatine monohydrate raw material is fed into the feeding hopper through the two rotating spiral feeding rods. And the screened creatine monohydrate raw material is dispersed and thrown out through the material guiding frame, so that the problem that the follow-up processing efficiency is poor due to the fact that the raw material is not dispersed in the feeding process of an existing feeding device and is excessively concentrated when being thrown into processing equipment is solved.

The utility model relates to the technical field of solution purification, and discloses a creatine monohydrate purification device capable of recycling mother liquor, which comprises a heat preservation enamel kettle shell, a stirring enamel kettle shell is fixedly connected in the heat preservation enamel kettle shell, and a driving end of a driving component is fixedly connected with a working gear I; a connecting shaft is rotatably connected to the interior of the gear protection block, a first transmission gear is fixedly connected to the exterior of the connecting shaft, a forward stirring shaft is fixedly connected to the interior of the first transmission gear, and a reverse stirring shaft is rotatably connected to the exterior of the forward stirring shaft. According to the utility model, the rotating motor is started to drive the working gear I, the working gear I drives the transmission gear I to rotate through the internal gear ring which is externally coupled and connected, then the transmission gear II which is connected with the bottom of the connecting shaft drives the working gear II to rotate, then the working gear II drives the forward stirring shaft, and the stirring fan blades are matched with the kettle bottom stirring block; and the solution is fully stirred.

This invention belongs to the field of organic synthesis technology, specifically relating to a creatine glycinate and its preparation method, comprising the following steps: pretreatment, drying creatine monohydrate, passing glycine through a 100-mesh sieve and storing it in a desiccator for later use, and selecting a reaction solvent; raw material dissolution, adding the reaction solvent to a reaction vessel, starting stirring and heating, adding creatine monohydrate, and stirring at a constant temperature until completely dissolved, finally obtaining a creatine solution; complexation reaction, adding glycine, increasing the stirring rate and heating after the addition is complete, maintaining the temperature for the complexation reaction, using staged stirring until the complexation reaction is complete; after the reaction is complete, using a gradient cooling method; crystallization and ripening, followed by constant temperature and low-speed stirring for 2 hours, then allowing the crystals to settle completely; after filtration, vacuum drying is performed to finally obtain creatine glycinate. This application solves the problems of uneven reaction, poor crystal quality, and low purity and yield in existing processes, achieving efficient and high-quality preparation of creatine glycinate.

This invention belongs to the field of organic synthesis technology, specifically relating to creatine nitrate and its preparation method, including the following steps: raw material pretreatment, pretreating creatine monohydrate; adding 600g of reaction solvent to a reaction vessel, stirring, adding 150g of purified creatine monohydrate from step 100, mixing evenly to obtain a reaction solution, and heating to 50-55℃; slowly adding 110g of 65% nitric acid dropwise to below the surface of the reaction solution, and after the addition is complete, maintaining the temperature at 50-55℃ for 2 hours to obtain a mixed solution; cooling the mixed solution to 0-5℃ at a cooling rate, adjusting the stirring rate, and stirring at a constant temperature for 2 hours to crystallize; filtering the above crystallization system, washing the filter cake 2-3 times with a cold solvent at 0-5℃; vacuum drying the filter cake, and sieving after drying to obtain the creatine nitrate product. This invention achieves efficient and stable preparation of creatine nitrate, significantly improving product yield and purity.

The utility model relates to the technical field of food processing, and discloses a granularity-adjustable creatine monohydrate special crusher which comprises a bottom plate, the top of the bottom plate is fixedly connected with a first supporting plate, the front side of the first supporting plate is fixedly connected with a fixing plate, the inner side of the first supporting plate is fixedly connected with a granularity-adjustable crushing mechanism, and the top of the bottom plate is fixedly connected with a second supporting plate. A first supporting plate is fixedly connected to the top of the fixing plate, a second supporting plate is fixedly connected to the top of the first supporting plate, a smashing pretreatment mechanism is fixedly connected to the inner side of the second supporting plate, the smashing mechanism comprises a smashing machine shell, the outer side of the smashing machine shell is fixedly connected to the inner side of the first supporting plate, and a driving assembly is fixedly connected to the top of the fixing plate. According to the creatine monohydrate crusher, the two connecting rods slide in the grooves formed in the connecting strips and the grooves formed in the crusher shell, the angle of the baffle is adjusted, the granularity of the crushed creatine monohydrate can be accurately controlled according to requirements, and the crusher can adapt to diversified production requirements.

The invention belongs to the technical field of nutritional supplements, and particularly relates to a nutritional supplement with stable performance and application thereof. The nutritional components comprise creatine monohydrate and a Chinese wolfberry fruit extract. Under a buffer system, the creatine monohydrate and the wolfberry extract in the nutritional supplement are mixed according to a ratio of (0.5-5): 1, so that the PCr and 1-RM power can be effectively improved, the decomposition of creatine can be greatly reduced, and a positive effect on maintaining active creatine is achieved. Experiments show that according to the nutritional composition, the increase amount of PCr is 14%-19%, the increase amount of 1-RM power is 6.1%-8.5%, the highest percentage of residual creatine can reach 94%-95%, and the content of active creatine is reserved to a great extent.

The invention relates to the technical field of nutritional supplements, and discloses a creatine-rich micro-effervescent tablet preparation process, the method comprises raw material pretreatment, wet granulation, fluidized bed embedding granulation, drying treatment and total mixing tabletting, and the creatine raw material (including creatine monohydrate and creatine hydrochloride) pretreatment standard is set, so that the creatine raw material (including creatine monohydrate and creatine hydrochloride) is obtained; and the conversion reference consistency of different batches of creatine raw materials is ensured. By capturing abnormal adhesive distribution signals in the wet granulation process in real time, a hot air supply and exhaust strategy is adjusted in real time, and it is guaranteed that the process balance point is rapidly recovered under the abnormal working condition of the creatine hydrochloride granulation process; meanwhile, a crystal water removal state is synchronously monitored in a fluidized bed embedding granulation link, so that whether a temperature control deviation problem occurs in a creatine monohydrate dehydration process or not can be dynamically identified, the stability of converting creatine monohydrate into anhydrous creatine is guaranteed, and the process fluctuation risk of disintegration time limit of the effervescent tablets is reduced from the source.

Provided herein is an exercise supporting nutritional supplement with an associated delivery platform, method, and system. As disclosed the exercise supporting nutritional supplement may comprise some or all of Agmatine Sulfate, Betaine Anhydrous, Choline (as Choline Bitartrate), Citrulline, Creatine Monohydrate, Beta Alanine, L-Tyrosine, Choline Bitartrate, Bovine Collagen, Caffeine Anhydrous, Pink Himalayan Salt, and Black Pepper Extract.

The utility model relates to the technical field of stirrers, and discloses a creatine monohydrate crystal processing device capable of accurately controlling temperature, which comprises a box body, a sliding sleeve is fixedly connected to the inner wall of the box body, two fixing blocks are fixedly connected to the outer part of the sliding sleeve, a sliding ball is rotatably connected to the inner wall of the sliding sleeve, and the sliding ball is fixedly connected to the inner wall of the box body. The end, away from the fixing block, of the sliding ball is fixedly connected with a rotating column, the outer portion of the rotating column is movably connected with a clamping sleeve, the inner wall of the clamping sleeve is movably connected with a first clamping ring, the end, away from the rotating column, of the clamping sleeve is fixedly connected with a fixing ring, and the end, away from the first clamping ring, of the clamping sleeve is movably connected with a second clamping ring. The motor drives the rotating column to rotate, the rotating column extrudes the clamping sleeve, the clamping sleeve is connected with the fixing ring, and the first clamping ring and the fixing ring deform to apply pressure to the fixing ring, so that the internal sealing effect is improved, the rotating column is stabilized, and the abrasion degree of the rotating column is reduced.

The dialysis solution is used in the prophylaxis and treatment of creatine deficiency in patients and comprises one or more creatine compound(s) selected from the following groups: (i) (phospho)creatine and the physiologically acceptable salts thereof, in each case together with any desired proportions of water of crystallization, in particular creatine monohydrate; and (ii) guanidinoacetic acid (physiological precursor of creatine) and the physiologically acceptable salts thereof, in each case together with any desired proportions of water of crystallization. The one or more creatine compound(s) is / are present in the dialysis solution in a concentration equivalent to 0.8 to 2.5 mM creatine. The dialysis solution additionally has a concentration of 0.1 to 200 μpM creatinine.

The invention provides a creatine compound B vitamin composition and a preparation method thereof. The creatine compound B vitamin composition is prepared from the following raw materials in parts by weight: 50 to 70 parts of creatine monohydrate, 4 to 20 parts of compound B vitamin microcapsules, 15 to 40 parts of silicified microcrystalline cellulose (SMCC) and 0.5 to 1.5 parts of magnesium stearate. The creatine and the vitamins play a synergistic role, the compatibility and the stability of all the components are remarkably improved by optimizing the composition and the proportion of the raw materials and combining a special preparation process, and the bioavailability of the creatine is improved. The composition provided by the invention can effectively improve athletic performance, promote muscle recovery and meet nutritional requirements of different people.

The application provides a high-stability creatine monohydrate composition and a preparation method thereof, and comprises core material and coating material; the core material comprises modified silicon dioxide 10-50 parts, creatine monohydrate 1-5 parts, a filler 10-50 parts and a binder 1-5 parts; the coating material comprises polyacrylic resin II 1-10 parts and a film-forming aid 1-20 parts; wherein the modified silicon dioxide is a product of KH570 grafted silicon dioxide and copolymerization of methacryloxypropyl double-terminated polydimethylsiloxane. The added modified silicon dioxide has a super large specific surface area, can firmly adsorb creatine monohydrate on the surface and enhance the stability of creatine monohydrate; meanwhile, through copolymerization with methacryloxypropyl double-terminated polydimethylsiloxane, the modified silicon dioxide forms a stable three-dimensional network structure of organic silicon, can wrap the adsorbed creatine monohydrate inside and further enhance the stability of creatine monohydrate.

The invention discloses functional soft sweets with creatine and a preparation method of the functional soft sweets, the soft sweets comprise 20 to 35 parts of deionized water, 40 to 65 parts of maltitol liquid, 20 to 30 parts of creatine monohydrate, 8 to 15 parts of white granulated sugar, 0.5 to 1 part of sodium citrate, 1 to 3 parts of compound stabilizer, 0.01 to 0.03 part of stevioside, 0.1 to 0.8 part of acid liquor, 0.01 to 0.07 part of food coloring and 0.1 to 0.5 part of edible essence, the creatine monohydrate is subjected to superfine grinding, and the particle size D90 of the creatine monohydrate is less than or equal to 20 microns. The soft sweets are compounded by the maltitol liquid, the white granulated sugar, the stevioside, the creatine monohydrate and other components, so that the soft sweets have the following characteristics that the soft sweets are soft and glutinous in mouth feel and moderate in sweetness, have sour and sweet flavor, and contain rich creatine and other functional components; the requirements of fitness people and people paying attention to health on energy supplement, muscle recovery, immunity improvement and the like can be met.

This invention provides a creatine citrate and its preparation method. In this method, creatine monohydrate is used as the creatine source, and creatine monohydrate reacts with citric acid in a reaction solvent. The creatine citrate is obtained through temperature-controlled reaction, temperature-controlled crystallization, filtration, and drying. The product obtained by this invention has a molar yield ≥90% and a purity ≥99.6%. The obtained creatine citrate is a white crystalline powder and can be widely used in food and beverage additives, health products, pharmaceutical raw materials, daily chemical raw materials, and feed and veterinary drug additives.

The application provides a method for reducing the content of trace and trace impurities in creatine monohydrate, and relates to the technical field of chemical production.The method provided by the application reduces the content of trace and trace impurities in creatine monohydrate by inhibiting side reactions through a catalyst and reducing the content of trace and trace impurities in creatine monohydrate through recrystallization technology.The catalyst can not only catalyze the formation of non-radical to inhibit the generation of dicyandiamide from cyanamide radical, but also catalyze the oxidation of trace formaldehyde in sodium creatine to inhibit the generation of dihydrotriazine, and finally high-purity creatine monohydrate product can be produced through recrystallization.The content of dicyandiamide and creatinine in creatine monohydrate produced by the prior art is 300-400 mg·kg ‑1 , the content of dihydrotriazine is 20-30 mg·kg ‑1 , and these impurities are harmful to human body, so it is difficult to further reduce them by the prior art.The method provided by the application can reduce the content of dicyandiamide and creatinine in creatine to less than 50 mg·kg ‑1 , and the content of dihydrotriazine is reduced to less than 5 mg·kg ‑1 .

The invention belongs to the technical field of nutritional supplement chemical and chemical synthesis, and particularly relates to a creatine magnesium chelate and a preparation method and application thereof, and the preparation method comprises the steps of reaction solution preparation, mixing, chelation reaction, thermal microfiltration, anti-solvent crystallization, centrifugal recovery and vacuum drying. The method comprises the following steps: carrying out a low-temperature equimolar chelation reaction on creatine monohydrate and a specific magnesium salt under the conditions that the pH value is 7.0-8.0 and the temperature is 25-40 DEG C, carrying out thermal microfiltration on a solution after the reaction is completed through a microfiltration column, then cooling a filtered solution to 5-10 DEG C, carrying out an ethanol and acetone binary anti-solvent low-temperature precipitation purification process, centrifugally collecting crystals, and carrying out vacuum drying, so that the product purity is more than or equal to 98%, the yield is more than or equal to 85%, and the product purity is more than or equal to 90%. The obtained product shows a stable coordination structure, and is especially suitable for the production of sports nutritional supplements and medical magnesium supplements.

The invention discloses synthesis and application of a modified creatine monohydrate antibacterial surfactant, and belongs to the technical field of daily chemical products. The modified creatine monohydrate antibacterial surfactant is a symmetrical dicationic amphiphilic surfactant formed by a quaternization modified creatine dicationic structure through a connecting arm; and the connecting arm is obtained by reaction of hydroxyethyl ethylenediamine and glutaryl dichloride. According to the modified creatine monohydrate antibacterial surfactant, creatine molecules of natural sources serve as a structural framework, the antibacterial function and the surface activity are integrated through chemical modification, and the modified creatine monohydrate antibacterial surfactant is suitable for being applied to the fields of medical disinfection, daily chemical washing and care, biological materials and the like.

The invention discloses a diluent for sorting pig Y sperms as well as a preparation method and application of the diluent. The diluent is prepared from the following components: 40 g / L of glucose, 0.5 g / L of sodium citrate, 0.1 g / L of creatine monohydrate, 0.75 g / L of potassium chloride, 0.0015 g / L of rotenone, 2.38 g / L of HEPES, 0.2 g / L of magnesium chloride and 1.0 g / L of bovine serum albumin. The diluent can amplify the difference of linear movement speed between X and Y sperms of pigs by regulating ATP supply, and can separate the Y sperms with higher movement speed in combination with an upstream sorting method, and the separation efficiency reaches 70-80%. The diluent disclosed by the invention has the characteristics of simplicity, rapidness, high efficiency and low cost in Y sperm separation, is almost harmless to sperms, and is suitable for being applied to boar production.

The invention relates to the field of animal feeds, and discloses an astaxanthin-rich high-nutrition egg feed for egg gamecocks and a preparation process of the astaxanthin-rich high-nutrition egg feed for egg gamecocks, and the feed comprises the following components in percentage by weight: 1.0-3.0% of enzymolysis yeast or algae source astaxanthin biomass; the invention discloses an astaxanthin product coated with a liposome-chitosan composite micro-capsule. Functional additives such as L-arginine, creatine monohydrate and the like; and a basal feed matrix. The preparation process comprises the following steps: preparing an astaxanthin product coated with enzymolysis astaxanthin biomass and lipidosome-chitosan composite micro-capsules; mixing the basic feed components with the enzymolysis astaxanthin biomass and the like, and then performing low-temperature granulation; and then performing vacuum dynamic coating on the obtained basic particles, and spraying liquid containing the microcapsule astaxanthin and other thermosensitive active ingredients. The stability and bioavailability of astaxanthin and other active ingredients in the feed processing and storage process and the animal digestion process are remarkably improved, deposition of astaxanthin in egg yolk is effectively promoted, and the quality of egg products is improved.

This invention provides a tricreatine malate and its preparation method. The method uses creatine monohydrate and malic acid as raw materials, and prepares tricreatine malate in a reaction solvent through a temperature-controlled reaction, low-temperature crystallization, filtration, and drying process. The preparation method provided by this invention yields a product with a molar yield ≥90% and a purity ≥99.7%. At 20°C, the solubility of tricreatine malate in water is 6 g / 100 ml. This tricreatine malate is a white crystalline powder with a malic acid odor and the advantages of high creatine content and high solubility. As a pharmaceutical raw material and food / health product additive, it can reduce the dosage, improve taste, and lower costs.

The invention discloses a synthetic method of creatine, which has the advantages of simple reaction conditions, high yield, convenience in operation and the like. Particularly, in the sarcosine preparation process, the pH value is adjusted through ammonia water, cyanamide is dropwise added for reaction, and after the reaction is completed, the ammonia water is recycled for use; and finally, adjusting the pH to be neutral with hydrochloric acid, cooling, separating out a creatine crude product, and filtering to obtain a product. The mother liquor contains ammonium chloride which is recycled by fertilizer manufacturers, and basically no wastewater is generated. The alkalescent ammonia water is adopted to adjust the pH value, cyanamide basically does not generate dicyandiamide, and the defect that cyanamide is easily polymerized into dicyandiamide when sodium hydroxide is adopted to adjust the pH value in an existing method is overcome. According to the method, the raw material cyanamide is high in utilization rate, high in yield, few in impurity and high in purity, the molar yield can reach 90%, and the product purity is 99.9% or above. Therefore, the preparation method of creatine monohydrate provided by the invention has very high application value.

The invention relates to the technical field of creatine monohydrate processing, and discloses a creatine monohydrate distribution bin pneumatic gate precise discharging control device which comprises a distribution bin mechanism, a precise discharging control mechanism is fixedly arranged at the bottom end of the distribution bin mechanism, and the bottom end of the precise discharging control mechanism is connected with a capacity control mechanism. The precise discharging control mechanism comprises a positioning frame and a positioning column, a positioning ring is fixedly arranged at one end of the positioning frame, a rotating disc is rotationally arranged in the middle of the positioning ring, and the bottom end of the rotating disc communicates with a plurality of material control barrels. The scraper is combined to scrape redundant powder, so that the accurate amount of discharging each time is ensured, and the problem that the discharging amount is not accurate is effectively solved; the discharging amount is controlled through a mechanical structure, and the speed does not need to be reduced in the discharging process, so that the discharging efficiency is remarkably improved while the discharging precision is guaranteed, and the packaging discharging time is shortened.

Composition containing alkaline stabilizers (10) for encapsulating creatine hydrates, characterized by that the composition (10) for encapsulating creatine hydrates comprises a hydrogel encapsulation structure (11) and a plurality of creatine composition units (12), wherein each creatine composition unit (12) consists of a creatine monomer (121) and an alkaline stabilizer (122), wherein the hydrogel encapsulation structure (11) is capsule-shaped and has a three-dimensionally cross-linked gel matrix (11), wherein the creatine monomer (121) comprises 50-99.99% and the alkaline stabilizer comprises 0.01-50% of the creatine composition unit (12), wherein the creatine composition units (12) are encapsulated in the gel matrix (11); that the base material of the gel matrix (11) is selected from the group consisting of gum arabic, pectin, guar gum, locust bean gum, gellan gum, carrageenan, agar, xanthan gum, carboxymethylcellulose, gelatin, fucoidan, modified starch, starch, maltodextrin and poorly digestible maltodextrin; that the creatine monomer (121) is a variety of creatine molecules; and the alkaline stabilizer (122) consists of a variety of alkaline metal ions or their compounds.