The present disclosure relates to a communication method and system for converging a 5th-Generation (5G) communication system for supporting higher data rates beyond a 4th-Generation (4G) system with a technology for Internet of Things (IoT). The present disclosure may be applied to intelligent services based on the 5G communication technology and the IoT-related technology, such as smart home, smart building, smart city, smart car, connected car, health care, digital education, smart retail, security and safety services. Embodiments of the present invention provide a multiple access method, a multiple access transmitter and a multiple access receiver. The multiple access method comprises the steps of: performing, by a transmitter, channel coding on a bit sequence to determine a coded sequence; interleaving and/or scrambling the coded sequence, and performing multidimensional constellation modulation on the interleaved and/or scrambled sequence; performing grid mapping on the modulated symbol sequence to determine a mapped sequence, and transmitting the mapped sequence; receiving, by a receiver, mixed signals from multiple transmitters, the mixed signals are obtained by performing, by each of the multiple transmitters, interleaving and/or scrambling, multidimensional constellation modulation and grid mapping on data; and, decoding, by the receiver, mixed information according to interleaver information and/or scrambler information, multidimensional constellation information and grid mapping pattern information corresponding to each transmitter to obtain data corresponding to each transmitter.