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1 results about "Logistic distribution" patented technology

In probability theory and statistics, the logistic distribution is a continuous probability distribution. Its cumulative distribution function is the logistic function, which appears in logistic regression and feedforward neural networks. It resembles the normal distribution in shape but has heavier tails (higher kurtosis). The logistic distribution is a special case of the Tukey lambda distribution.

A method and system for detecting impurities in flunarizine hydrochloride raw material.

PendingCN122306995AMathematical modelFlunarizine Hydrochloride
This invention provides a method and system for detecting impurities in flunarizine hydrochloride raw material. The detection method includes: acquiring the original chromatographic signal, performing empirical mode decomposition for denoising and baseline optimization to obtain a baseline-corrected and denoised chromatogram; determining the signal-to-noise ratio based on the energy relationship between noise and signal in preprocessing, determining the optimal analytical scale through a preset function, determining the number of chromatographic peak components by screening ridges through continuous wavelet transform, and extracting initial model parameters; establishing a mathematical model for the convolution of a standard Gaussian function and a modified Logistic distribution function for each component peak, using a trust-region reflection algorithm for nonlinear iterative fitting, with the objective function containing a least-squares residual term and a weighted regularization term; after the objective function converges, obtaining the optimal model parameters, and calculating the integral area of ​​each impurity component peak to determine its content.
Owner:ZHENGZHOU RUIKANG PHARM CO LTD