The invention discloses a method, a device and a system of pan tilt zoom (PTZ) control of a video camera based on kinect. PTZ control of the video camera for security and protection monitoring can be achieved through human movements, complex operation interfaces are not required, and PTA control of the video camera is operated simply and conveniently through a video monitoring system. The method, the device and the system comprise that the human movements are caught through the kinect, human movement vector quantity data are input into behavior identification software, after corresponding data optimization, data conversion and behavior judgment, the human movements are converted into PTZ control commands of the monitoring video camera, the PTZ control commands include upward shift, downward shift, left shift, right shift, picture enlargement, picture shrink, preset position switchover, windshield wiper starting and the like, the control commands are sent to the video camera to conduct PTZ control, the video executes corresponding movements, and operation results are displayed in real time through real-time video frames.