The invention discloses health-care noodles having the effect of resisting tumors and a making method of the health-care noodles. The health-care noodles having the effect of resisting tumors comprisethe following raw materials by weight: flour, sorghum flour, glutinous rice flour, buckwheat flour, vegetable juice, fleeceflower roots, glossy ganoderma, Chinese jujube powder, licorice roots, dandelions, chrysanthemums, Chinese wolfberry fruits, A. venetum L., ginkgo leaves, herba rhodiolae, honeysuckle flowers, bitter gourds, roots of clerodendrum inerme (L.) gaertn., panax pseudo-ginseng, commeline communis, cubeb litsea trees, a food additive and auxiliary materials. The health-care noodles can be used as a staple food, can also be used as a health-care food, can also be used as a nourishing food for tumor patients after radiotherapy and chemotherapy, are fresh in taste, are selected from raw materials of natural Chinese herbal medicines, and are safe to use. New taste of the health-care noodles is increased, Chinese herbal medicines are used for comprehensively preventing and treating tumors, and the health-care noodles are free from obvious toxic and side effects. Experiment proves that the health-care noodles have the effects of resisting bacteria, resisting viruses and restraining cancer, and have the functions of eliminating cancer toxins and improving the anticancer immunity of organisms.