The invention discloses a yarn mixing and twisting device which comprises a base, wherein a box body is arranged at the top of the base, a first motor is arranged in the base, a first rotating shaft is connected with one end of the first motor, a placing plate is arranged at one end of the first rotating shaft, fixing rods are arranged at the top of the placing plate, the outer surface walls of the fixing rod are sleeved with bobbins, limiting structures are arranged on the upper portions of the outer surface walls of the fixing rods in a sleeving mode, coils are arranged at the top of the placing plate, a supporting plate is arranged in the middle of the interior of the box body, a wire guide hole is formed in the middle of the supporting plate, a second motor is arranged at the top of one side of the box body, a second rotating shaft is connected with one end of the second motor, a winding roller is arranged at one end of the second rotating shaft, and a bearing is arranged at one end of the winding roller. According to the yarn mixing and twisting device, by arranging the placing plate, the fixing rods, the bobbins, limiting rings, fixing pins, ceramic pieces and rubber rings, the twisting efficiency and effect are improved, yarn strands are prevented from being abraded, the bobbins are prevented from falling off, the product quality is improved, the cost is reduced, and the high use value is achieved.