The invention relates to an antibacterial PA66 / ABS composite material. The antibacterial PA66 / ABS composite material is mainly prepared through blending the following ingredients in parts by mass and carrying out melting: 50-70 parts of polyhexamethylene adipamide, 10-30 parts of processing activator, 30-50 parts of acrylonitrile-butadiene-styrene, 5-10 parts of compatibilizer, 5-20 parts of toughener, 0.1-0.3 part of diffusion oil, 0.6-1.5 parts of antibacterial agent and 0.2-2 parts of auxiliaries. The antibacterial PA66 / ABS composite material is prepared through firstly, thoroughly mixing weighed polyhexamethylene adipamide, weighed processing activator, weighed acrylonitrile-butadiene-styrene, weighed compatibilizer and weighed diffusion oil in a high-speed mixer, then, adding the antibacterial agent and the auxiliaries into the mixture, and finally, adding the toughener into the mixture and carrying out thorough mixing, so as to obtain a premix; carrying out melt extrusion on the premix through a twin-screw extruder, and carrying out drawing, cooling and pelleting. The product provided by the invention has the advantages of easiness in processing, high antibacterial performance, excellent mechanical properties, and the like.