The invention provides a
polyvinylpyrrolidone modified
cerium-based UIO-66 nano material as well as a preparation method and application thereof, and relates to the technical field of nano materials, catalysts and antitumor drugs. According to the method,
cerium ions are used as
metal nodes,
terephthalic acid is used as an organic connector, a
crystal framework with a UIO-66 characteristic topological structure is formed, then,
polyvinylpyrrolidone is introduced into framework nano particles in situ through
solvothermal reaction, and the nano particles are prepared. Therefore, the
polyvinylpyrrolidone modified
cerium-based UIO-66 nano material which is uniform in morphology and good in
dispersity and has an efficient piezoelectric effect and
peroxidase activity is obtained. The cerium-based UIO-66 nano-material disclosed by the invention can obviously enhance the catalytic performance under remote and accurate regulation and control of ultrasonic
waves, and excites an additional biological
catalytic function, so that the defect of single treatment is overcome through multi-mechanism
synergy, and high-efficiency, low-
toxicity and controllable treatment on tumors is realized.