The invention belongs to the technical field of production of antifogging agents, and discloses a novel antifogging agent for vehicles, wherein the novel antifogging agent composition comprises, by weight, 1-2 parts of brominated acetylcholine, 1-2 parts of phenacetin, 1-3 parts of sodium lauryl sulfate, 1-3 parts of sodium secondary alkylsulfonate, 1-3 parts of fatty alcohol sodium isethionate, 0.5-2 parts of coconut oil fatty acid diethanolamide, 0.5-2 parts of hydroxy synthetic alcohol polyoxyethylene, 0.5-2 parts of alkyl glycoside, 0.2-1 part of sodium citrate, 2-7 parts of glacial aceticacid, 60-75 parts of anhydrous ethanol, 8-15 parts of hard water softener, 0.2-1 part of preservative, and 16-32 parts of water. The process of the novel antifogging agent comprises selecting materials, stirring, mixing the raw materials, filtering, and preparing the finished product. According to the present invention, the novel antifogging agent can rapidly remove mist, and has substantially improved durability and substantially improved low-temperature resistance.