The invention provides an intelligent box-type transformer substation. The intelligent box-type transformer substation comprises a protection mechanism, a high-pressure chamber, a pressure transformation chamber, a supporting mechanism and a low-pressure chamber, wherein the high-pressure chamber, the pressure transformation chamber and the low-pressure chamber are arranged on the lower side of the protection mechanism; the high-pressure chamber, the pressure transformation chamber and the low-pressure chamber are all assembled on the upper side of the supporting mechanism; the protection mechanism comprises expansion plates, first convex blocks, pull rods, first springs, pulling ropes, second springs, second convex blocks, grooves, a protective plate, a U-shaped cleaning rod, L-shaped positioning rods, third springs, a first circular gear and a second circular gear; and the supporting mechanism comprises sliding plates, motor, screw rods, pressing plates, connecting plates, fourth springs, supporting columns, base plates, moving wheels, a moving plate, an air bag, a connecting strip block and a rain baffle plate. Compared with the prior art, the intelligent box-type transformer substation has the following beneficial effects: the function of clamping and fixing can be realized, and meanwhile, the protection area can be expanded, quick cleaning is performed conveniently, the functions of protection, rain blocking and rapid heat dissipation are achieved, and movement is convenient.