An orthopedic fixation system fuses bone, bones, or bone pieces in a predetermined anatomical position. The orthopedic fixation system includes an implant that transitions between an unconstrained shape and a constrained insertion shape, a drill guide, first and second K-wires, and a cannulated drill bit. The drill guide and the first and second K-wires retain the bone, bones, or bone pieces in an anatomical position corresponding with the predetermined anatomical position. The cannulated drill bit fits over the first and second K-wires and drills, respectively, first and second drilled holes into the bone, bones, or bone pieces. After insertion of the implant into the first and second drilled holes, the implant attempts to transition from its constrained insertion shape to its unconstrained shape such that the implant continuously compresses the bone, bones, or bone pieces thereby holding the bone, bones, or bone pieces in the predetermined anatomical position.