7 results about "Dianhydrohexitol" patented technology

The present invention relates to a method for preparing polyestercarbonates based on cycloaliphatic diacids, at least one 1,4:3,6-dianhydrohexitol, and at least one additional aliphatic dihydroxy compound, the polyestercarbonates prepared according to the method, and molding compounds and molded bodies containing the polyestercarbonates. The method according to the invention is a direct synthesis in which all structural elements forming the subsequent polyestercarbonate are already present as monomers in the first process step. It is characterized by a specific ratio of 1,4:3,6-dianhydrohexitol to at least one additional aliphatic dihydroxy compound being advantageous.

The object of this patent application relates to the field of hexitol for use in the prevention and / or treatment of diseases and / or symptoms caused by anaerobic pathogenic microorganisms, and more specifically to monoanhydrohexitol, dianhydrohexitol, or combinations thereof for use in the prevention and / or treatment of such diseases and / or symptoms. In one embodiment, the object is isosorbide for use in the prevention and / or treatment of diseases and / or symptoms associated with obligate anaerobic pathogenic bacteria such as Fusonucleatum, Porphyromonas gingivalis, Veillonella parvula, and Parvimonas micra.

A polyol composition, a composition for polyurethane preparation comprising the polyol composition, and a battery module according to the present invention comprise a compound represented by chemical formula 1 (see the description of the invention). In addition, the polyol composition according to the present invention comprises a first unit derived from at least one type of 1,4:3,6-dianhydrohexitol and a second unit derived from an alkylene oxide, and has a degree of unsaturation of 0.02 meq / g or less according to the following measurement method (see the description of the invention).

The present invention provides, in part, dianhydrohexitol-based cationic lipids of Formula (I), and sub-formulas thereof: (I), or a pharmaceutically acceptable salt thereof. The present invention also provides, in part, dianhydrohexitol-based cationic lipids of Formulae (IIA), and sub-formulas thereof: (IIA), or a pharmaceutically acceptable salt thereof. The present invention also provides, in part, dianhydrohexitol-based cationic lipids of Formulae (IIB), and sub-formulas thereof: (IIB), or a pharmaceutically acceptable salt thereof. The compounds provided herein can be useful for delivery and expression of mRNA and encoded protein, e.g., as a component of liposomal delivery vehicle, and accordingly can be useful for treating various diseases, disorders and conditions, such as those associated with deficiency of one or more proteins.

The present disclosure relates to 1,4:3,6-dianhydrohexitol, specifically isosorbide, and compositions comprising 1,4:3,6-dianhydrohexitol for treating oral inflammatory conditions. These conditions, which include both oral mucosal inflammation and periodontal diseases, are characterized by elevated levels of pro-inflammatory mediators, particularly IL-1 alpha and IL-8. Using the EpiOral™ model, isosorbide has demonstrated significant ability to reduce IL-1 alpha secretion and IL-8 gene expression in inflamed oral epithelial cells. These results support its therapeutic relevance in treating oral inflammatory conditions through modulation of key inflammatory mediators.

The present invention relates to a process for preparing a polyester carbonate comprising at least one 1, 4: 3, 6-dianhydrohexitol by melt transesterification reaction wherein the process comprises reactions in a specific chronological order. The obtained polyestercarbonate has good color and high molecular weight. Furthermore, the present invention relates to a polyester carbonate obtained by said method and to a molded body comprising the polyester carbonate.

An object of the present application is a composition comprising a compound having at least one heterocyclic ring and at least one antioxidant selected from the group consisting of antioxidants having at least two aromatic rings. In particular, the compound is selected from the group consisting of dianhydrohexitols, most particularly isosorbide. The compositions exhibit improved oxidation resistance, as well as lower yellowing during storage and after heat treatment. These compositions are useful in the preparation of polymers comprising isosorbide as comonomer.