A radio operated data card whose outer jacket forms a sealed protected housing for internal electrical components, including an RFID integrated circuit which incorporates data storage and a radio frequency transceiver, and one or more on-card antenna structures. Manually operated electrical switching elements, or antenna structures which are responsive to the positioning of conductive members, such as the human hand, at particular locations on or near the surface of the card, are connected to the on-card electronic circuitry. The switching elements or antenna elements are selectively operated by the cardholder who manipulates the card in predetermined ways to generate data signals that may be used to activate the card, store data in the card, or transmit data to the reader.