The invention discloses a method for color
standardization of
pathological image based on low rank embedded non-negative
matrix decomposition, the data of two
pathological images are expressed in theform of
observation matrix, which are converted into
optical density, the low rank representation matrices of the source
optical density matrix and the target
optical density matrix are solved respectively, the corresponding optical
density matrix is decomposed into an RGB color matrix of each
dyeing component and an intensity matrix of each pixel under each
dyeing component, At last, that image is convert to RGB form, so as to achieve the color
standardization from the source
pathological image to the target pathological image, the invention can be used for color
standardization of pathological images and improvement of
visualization effect, Avoiding the color inconsistency of pathological images caused by different pathological scanners, different laboratory
staining methods and different
staining ratio has important significance for pathological image imaging,
staining separation and intelligent pathological
image analysis, and has broad market prospects and application value.