43 results about "Odds ratio" patented technology

We analyzed bone marrow from 67 patients from a phase 2 study of farnesyltransferase inhibition with tipifarnib (R115777, ZARNESTRA®), in older adults with previously untreated, poor-risk acute myeloid leukemia (AML) for N-Ras mutations, global gene expression, and/or quantitative PCR (qPCR) of specific genes. Microarray profiling identified a two-gene expression ratio (RASGRP1:APTX) which provided the greatest accuracy for predicting response to tipifarnib. We demonstrated that this classifier could predict response to tipifarnib in an independent set of 54 samples from relapsed or refractory AML, with a NPV and PPV of 92% and 28%, respectively (odds ratio of 4.4). Therefore, in both newly diagnosed and relapsed or refractory AML, this classifier improves the overall response rate by approximately 50% while maintaining a high NPV, and significantly improves patient overall survival. The two-gene classifier was also validated by qPCR in thirty AML samples from the same clinical study demonstrating a negative predictive value (NPV) and positive predictive value (PPV) of 81% and 50%, respectively (odds ratio of 4.3). These data indicate that a simple two-gene expression assay may have utility in diagnosing a population of AML patients who are more likely to respond to tipifarnib.

The present apparatus includes: an intensity ratio calculation unit configured to calculate a first and a second intensity ratios which are ratios of Stokes light intensity to anti-Stokes light intensity obtained when a light pulse is output to a first end and a second end of an optical fiber, respectively; a temperature calculation unit configured to calculate a temperature distribution along the optical fiber based on a reference temperature, the first and the second intensity ratios, and a total length loss ratio, which is a loss ratio of Stokes light to anti-Stokes light with regard to a total length of the optical fiber; and a total length loss ratio calculation unit configured to calculate the total length loss ratio based on the first and the second intensity ratios with regard to a location in a predetermined section close to both ends of the optical fiber whose temperature is kept constant.

A method of improving the loss ratio on a book of insurance including the use of a computer data base with a user interface display including questions for insured entities making up the book of insurance. Spaces are provided on the display for the input of answers from an insured. A survey is used to question the insured entity, the survey eliciting answers to the questions posed. Data is input from the answers received into the computer data base at the spaces provided for. The answers that are collected are compared with answers contained in written documents having information that was supplied by a third party insurance underwriter. Inconsistent answers are identified and the information obtained is reported to the underwriter who can determine whether or not the insurance premium of the insured should be adjusted.

The invention discloses an online loss calculation method for a modular multilevel converter (MMC), and belongs to the field of power transmission and distribution. The method comprises the following steps of: 1) calculating the conduction loss of two insulated gate bipolar transistors (LGBT) and two flywheel diodes in each sub-module (SM); 2) calculating the switching loss of the two IGBTs and the reverse recovery loss of the two flywheel diodes in each SM; and 3) calculating related loss by using a loss calculation module. The method has the advantages that: 1, the complexity of manual measurement and calculation is effectively avoided when the MMC has a great number of modules, workload is greatly reduced, and the method is fast and convenient; 2, the online calculation of the loss of the MMC is realized, and the method is wide in application range, and can be applied to the loss calculation of an MMC system in any operating state; and 3, modular packaging is facilitated, a floor area is saved, the utilization rate of resources is increased, and the output of a platform comprises various kinds of loss and loss ratios, so that the method is direct and clear, and staff can conveniently observe the running state of the system at any time.

Methods and computer readable media for statistically identifying an increased risk for disease. In one embodiment, resampling techniques are utilized to consider different genotype combinations within a resampling subset of a case/control data set. Odds-ratios and theoretical p-values are calculated for each genotype combination so that an increased risk of disease associated with a particular genotype combination may be identified. In another embodiment, different genotype combinations within a case/control data set are considered. Odds ratios are calculated for each genotype combination. Empirical p-values are calculated for the odds ratios through randomization techniques. Using the odds-ratios and/or empirical p-values, an increased risk for disease associated with a particular genotype combination may be identified.

The embodiment of the invention provides a lawyer recommendation method and system, which belongs to the technical field of data processing. The method comprises the steps that target action cause information corresponding to a user is acquired; a target arbitration document meeting preset similarity is acquired from an arbitration document database stored in the storage unit of an electronic device based on the target action cause information; and finally at least one recommended lawyer recommended to the user is acquired from lawyers in the target arbitration document. The recommended lawyeris the most similar lawyer who processes the target action cause information, and the recommended lawyer has a higher odds ratio. The user has a higher odds ratio. At least one recommended lawyer recommended to the user is acquired from lawyers in the target arbitration document, which can effectively improve the accuracy and efficiency of lawyer recommendation.

The invention concerns a sputtering target composed of an Mo alloy containing at least one metal from group 5 of the periodic table, the mean content of group 5 metal being between 5 and 15 at% and the Mo content being >= 80 at%. The sputtering target has a mean C / O ratio in (at% / at%) of >= 1. The claimed sputtering targets can be produced by shaping and have improved sputtering behaviour.

The present invention relates to a liver cancer prediction system for early detection and control method thereof, which can perform hierarchical classification relating to a risk group for hepatocellular carcinoma, through an estimation of the incidence rate for the hepatocellular carcinoma and a relative risk of the incidence of hepatocellular carcinoma, both of which are found on an individual basis. General information on a patient, information depending on an ultrasonic test performed, clinical information including information on findings upon a first registration of a patient and information on findings upon a diagnosis of liver cancer, and information on a risk group, are stored in a database. A regression count which is an attributable ratio corresponding to each of risk factors is calculated based on the clinical information and risk group information stored in the database. An odds ratio of the incidence of liver cancer is measured by calculating risk probability of the incidence of liver cancer through a given operation process using the calculated regression count. It is thus possible to prevent the incidence of liver cancer per person depending on prediction of the incidence of liver cancer. Also hierarchical classification relating to a risk group for hepatocellular carcinomas is performed through the incidence rate for hepatocellular carcinoma and a relative risk of the incidence of liver cancer that are calculated on an individual basis. Therefore, a tailored model for prediction the incidence of liver cancer can be constructed.

Systems and methods for positioning bilinear texture samples to produce an anisotropically filtered texture mapped pixel may improve texture mapping performance and image quality. The bilinear texture samples are positioned along a major axis of anisotropy to approximate an elliptical footprint, ensuring that the bilinear texture samples span the entire axis of anisotropy without extending beyond the major axis of anisotropy. An additional bilinear texture sample or a pair of additional bilinear texture samples is positioned in the center of the axis of anisotropy dependent on the anisotropic ratio. The additional bilinear texture samples are weighed less than the other bilinear texture samples and all of the bilinear textures samples lie within the anisotropic footprint.

The present invention provides a method of discriminating a relative risk for the morbidity of atopic dermatitis of a test subject comprising: analyzing gene polymorphism of two or more of genes related to onset of atopic dermatitis using a sample isolated from a statistically significant number of normal persons and patients of atopic dermatitis to determine relative ratios (percentages (%)) related to the individual gene polymorphism of individual derived from the analysis; and calculating an odds ratio according to specified gene polymorphism from the relative ratio; and using, as a discrimination criterion, a combination of two or more of gene polymorphisms showing a synergetically higher odds ratio than odds ratios according to individual gene polymorphism. The method is useful for predicting susceptibility of an AD patient to chemicals based on genes and for selecting the diagnostic and/or therapeutic agent by eliminating harmful drug reactions from the analysis of principal factors related to onset and development of AD and interaction among these genes, and for determining a diagnostic method and therapeutic method using the detection method of morbidity risk.

The invention provides a process of screening gene chip diversity expression gene, relating to an algorism for screening diversity expression gene in gene chip diversity expression analysis. The invention comprises following steps that firstly normalized processing chip data, secondly building up linear mold of logarithmic proportionality x ij= mu + mu j + epsilon, thirdly calculating globe mean value mu and the values of column effect mu j and variance sigma, fourthly calculating 2*ln (odd ratio) of each gene through utilizing mu, mu j and sigma, and fifthly setting localized value of X2 cutoff and n, and the gene of n is defined as diversity expression gene when the value of 2*ln (odd ratio) in the fourth step is larger than X2 cutoff. The invention designs appropriate statistic throughbuilding up statistical mode, and finally provides a significant probability numerical value for each gene as the standard of screening gene through utilizing the method of hypothesis test. The process overcomes the weaknesses that the conventional multiple process is lack of statistics basis and is difficult to assess the sensibility and specificity of the algorism self.

An application operating on a portable computing device that generates a suggested hypothesis of at least one of: a diagnosis, a treatment, and subsequent medical investigation. The application receives quantified subfactors, collectively defining factors, for each patient. Subfactors of the medical condition are related to the history, symptoms, signs, tests, and responses to the treatment. The application determines an odds ratio for each factor regarding each hypothesized medical condition as well as an associated prevalence. The application can also determine a respective sensitivity and specificity. Posterior probability distribution, such as using Bayesian statistics, can be applied using odds ratios, prevalence, sensitivity specificity, and the associated correlations to determine the suggested hypothesis of the diagnosis, treatment, and any next tests.

The invention relates to the technical field of livestock breeding, in particular to a full-automatic feeding system for liquid fodder feeding in a pig farm. The system includes a fodder blending tank, a storage tank, a water storage container, a cleaning water pump, a fodder acquirement water pump, multiple dry fodder towers, a high-pressure draught fan, a plurality of feeding stations, an air pump, a plurality of pneumatic valves and a PLC device. The feeding system for liquid fodder feeding runs in a full-automatic mode without management of staff, as long as there are electric power, waterand dry fodder, liquid fodder feeding can be automatically and accurately completed, not only can it ensured that a water-fodder ratio and the feeding frequency meet the demands of live pigs in different growth periods, but also the operating cost of the pig farm can be greatly reduced, and the feeding efficiency of the liquid fodder is improved.

The invention discloses an upgrade digital code input method with number as code to input character, which comprises the following steps: (1) inputting with writing mode; dividing the number to upper and lower zone; dividing all pencil-type of character to five type stroke; fetching code according to radicals or stroke; proceeding code fetching input separately at upper or lower position of the character; (2) inputting with spelling type; dividing 26 alphabet to 10 groups; using number as code of each group; inputting into character; ranging with English ABCD order; (3) pressing ' +' key as all code inputting at any inputting type; This invention uses number to replace code, which possesses convenient operation, low repeated code ratio, little code position and wide application area.

Reflector antennae and related structures and methods are described. The reflector antennae may have a deep f/D ratio and use an offset corrugated horn. Pivoting feed arms may be included for connecting a feed horn to a dish of the antenna. Radomes are also described, which may be formed of two or more pieces.

The invention relates to a method for predicting re-pregnant vaginal birth after cesarean delivery. The method comprises the following steps: S1: collecting a large number of clinical data of pregnant and lying-in women experiencing re-pregnant trial vaginal birth after cesarean delivery; S2: comparing the clinical data of two groups of pregnant and lying-in women, screening independent influence factors for influencing successful re-pregnant trial vaginal birth after cesarean delivery, and calculating an odds ratio (OR) of each influence factor; S3: grading and classifying the independent influence factors, scoring the obtained odds ratios (OR) in combination with Logistic regression analysis so as to establish a predictive scoring table used before the re-pregnant vaginal birth after cesarean delivery; S4: according to the predictive scoring table, scoring the collected independent influence factors of each pregnant and lying-in woman, calculating a total score value, and drawing the total score values of all the pregnant and lying-in women into an ROC (receiver operating characteristic) curve to obtain an optimal critical score value, namely a cut-off point, wherein the cut-off point is a critical score value for judging whether a pregnant woman can accomplish the vaginal birth. By the method, a safe and feasible before-birth predictive scoring model for VBAC (vaginal birth after cesarean delivery) is established.

The invention discloses a bingo game machine having dynamic payment. A console provides the number of colored balls and the number of at least one winning round. An operation element computes based on the number of the colored balls and the number of the at least one winning round so as to generate actual loss ratio or extra reward of the at least one winning round. And a payment element conducts payment. When more than one winning round occur, the operation element, based on the number of the colored balls and the number of the winning rounds, generates candidate loss ratios, and any one candidate loss ratio is randomly selected from the candidate loss ratios to serve as the actual loss ratio, or rewards are taken from a reward pool with a designated proportion for even distribution to serve as the extra rewards of the more than one winning round. Therefore, according to the invention, the bingo game machine can control the magnitude of the loss ratios of the candidate loss ratios and provide dynamic actual loss ratios or extra rewards when there is more than one winning round by random selecting or controlling the number with the designated ratio, such that people are more attracted to bingo.

The current invention describes a method for selecting a particular population of women having a risk of developing obstetric or gynecologic pathologies indicated as odds ratio (OR) value higher than 5.5, comprising the following steps in order: a) determination of the levels of sialidase by means of the procedure described in Cauci et al. Am J Obstet Gynecol 1998; 178; 511-5 and/or prolidase activity by means of the procedure described in Cauci et al. J Infect Dis 1998; 178; 1698-706 in samples of body fluid; b) determination of the pH value of said body fluid samples; c) selecting the samples having a sialidase value equal or above 5.0 nmol of methoxyphenol and/or a prolidase level equal or above 1500 mOD for prolidase and a pH≧5.0. Consequently, this method gives the physician an efficient tool to decide whether or not to administer a pharmacological therapy to women at risk of severe adverse outcomes.

A reorganization of genomic data into a simpler standard form leads to more transparent data analyses. The customary selection practice that focuses on high odds ratios loci is shown to be biased, reflecting quality of presently reported risk loci for T2D. A selection criterion, based on Shannon information theory, brings clarity to this issue and provides a rational and optimal basis for selecting potential risk loci. This is used to determine an optimal disease classifier. Within the framework of the FUSION database this leads to a relatively successful degree of T2D prediction and nearly an order of magnitude more effective in detecting T2D. Chromosome 7 is strongly associated with T2D. A hypothesis of this study is that the genomic disease signal is possibly weak, and instead of focusing on individual loci a collection of loci contribute to a composite Score, which functions as the determinant of disease or its absence.

The invention discloses a portable device and a method for detecting the freshness of eggs on the basis of weight-loss ratios, and relates to weight-loss ratio detection, computers and agricultural product nondestructive detection technologies. The portable device comprises an egg and is provided with a shell, a long and short axis measuring module, a data line, an electric push rod, an embedded mainboard of a RAM (random access memory) architecture, a touch display screen, a power key, a start key, a stop key, a power line and a power supply battery. The method includes 1, arranging the to-be-detected egg on an egg weight detection opening in the long and short axis measuring module; 2, allowing a push plate to move so as to shift the egg to a specified position; 3, selecting mathematical models and processing acquired data; 4, displaying corresponding results on the screen. The portable device and the method have the advantages that the freshness of the eggs can be quickly nondestructively detected by the aid of weight-loss-ratio technologies, the portable device is simple in structure and low in cost and can be widely applied; the portable device is small and is easy to carry and popularize and applicable to large quantities of scenes.

The invention relates to a method for calculating a head-to-body ratio generated by a virtual image. According to the method, a depth map and two color images (one is a low-definition ILD image and the other is a high-definition Ihd image, wherein the low-definition image is registered with the depth map) are obtained. The method for obtaining the ratio of the distance of the outer canthus of a human body to the height of the human body comprises the following steps of calibrating the focal length f of a high-definition camera in the direction of the double-eye connecting line; extracting thefeature point lld of a human face in the low-definition image; extracting the feature point lhd of the human face in the high-definition image; extracting the average depth ddepth of the two eyes in the depth map, so as to obtain the feature points lld of two eye positions; calculating the pixel euclidean distance dpixel between the feature points of two outer canthus in the human face in the high-definition image lhd; calculating the physical distance dphysics between the two outer canthus; and calculating the ratio alpha of the distance between the two outer canthus to the height of the human body. The method is fast in image acquisition speed and can quickly complete the human body five-sense measurement. In addition, during the image acquisition process, no radioactive substance is generated, so that the method is harmless to the human body. Meanwhile, the human body does not need to be in the naked state or worn in the approximately naked way. Therefore, the privacy of the human body is protected. The collection and the measurement do not need to be completed in a closed environment, so that the dimension space is saved. The method is beneficial to the mental states of measured people.

A plasma display, a controller therefor and a method of driving determines a screen load ratio from a plurality of video signals input during one frame, and determines a total number of sustain pulses according to the screen load ratio. A ratio of overlap sustain pulses to non-overlap sustain pulses is determined according to a first load ratio, and the overlap and non-overlap sustain pulses are arranged according to the determined ratio. The first load ratio may be the screen load ratio or a display load ratio. The arranged sustain pulses are applied to a plurality of first and second electrodes that perform a display operation during a sustain period.