The invention discloses a three-dimensional stress sensor based on a circularly polarized liquid metal antenna. The sensor comprises a box body, a shell and a circularly polarized antenna structure body; six surfaces of the box body are symmetrically provided with orifices, the inner side of the surface where each orifice is located is fixedly provided with the shell, the circularly polarized antenna structure body is installed in an inner cavity of the shell, the upper top surface of the circularly polarized antenna structure body clings to an upper cover, the upper cover slidably covers theupper opening of the shell, and the upper cover extends out of the box body; the circularly polarized antenna structure body is a compressible organic polymer body, an annular micro-channel is formedin the organic polymer body, the annular micro-channel is filled with liquid metal serving as an antenna, two ports of the liquid metal antenna are correspondingly connected with two feeder lines, andthe feeder lines are led out from the side wall of the organic polymer body. The invention can remotely monitor the three-dimensional stress change in the rock-soil body in real time, and has the advantages of accurate signal receiving, high stability, small size and the like.