958results about How to "Eliminate generation" patented technology

The present invention provides a method for making a large nucleic acid having a defined sequence in vivo. The method combines recombineering techniques with a CRISPR / Cas system to permit multiple insertions of defined sequences into a target nucleic acid at one time, double stranded cleavage of target nucleic acids in which the defined sequences were not successfully inserted, and selection of successful recombinant cells. The method further includes repeating the process one or more times, using a successful recombinant from one round as the host cell for the next round.

Disclosed herein is a flat panel display manufacturing apparatus in a predetermined process is performed using plasma generated therein. In such a flat panel display manufacturing apparatus, a process gas is supplied into a chamber in an evenly diffused state to generate even plasma inside a symmetrical interior space of the chamber. Consequently, the flat panel display manufacturing apparatus can appropriately control flow rate of the plasma, thereby being capable of performing even processing on a large-scale substrate. In the flat panel display manufacturing apparatus, a substrate pedestal thereof is provided with a combination of vertical and horizontal shielding members, thereby being entirely protected from attack of the plasma, resulting in an increased life-span.

A fabric for a papermaking machine is configured as a belt, the two side edges of which are configured in each case as closed lines. Furthermore, the belt is formed in one layer from a solid material and has pores which form passages between the two surfaces of the belt. The belt has regions with a width of approximately 400 micrometers (μm) or less. These regions extend in the longitudinal direction over the entire circumference of the belt, transversely with respect to the side edges, and include no pores formed therein.

A method of manufacturing a dye-sensitized photoelectric conversion device is provided by which a dye-sensitized photoelectric conversion device being excellent in strength and durability and free of any projection, as a result of the absence of need for an end seal, can be fabricated through simple manufacturing steps. In manufacturing a dye-sensitized photoelectric conversion device which has an electrolyte between a dye-sensitized semiconductor layer and a counter electrode and which also has a first armor member provided on the outside of the dye-sensitized semiconductor layer and a second armor member provided on the outside of the counter electrode, a sealing material and the electrolyte are formed at predetermined locations of one or both of the first armor member and the second armor member, thereafter the first armor member and the second armor member, with the sealing material and the electrolyte sandwiched therebetween, are adhered to each other with the sealing material under a gas pressure of not higher than the atmospheric air pressure and not lower than the vapor pressure of the electrolyte.

A tri-leaflet heart valve includes an annular valve base with an inner surface forming an orifice through which blood flows from the upstream side to the downstream side. Three protruding hinges, each with concave sockets on opposite sides, are formed on the inner surface. Each hinge has a downstream face and an upstream face connected by a ridge. Three leaflets are respectively arranged between adjacent hinges. Each leaflet has round pivots on both sides that rest inside the concave sockets, allowing the leaflets to freely rotate in the annular valve base. When the leaflets are subject to a positive pressure from the blood flow, the leaflets are pushed open and allow a central flow. When the leaflets are subject to a negative pressure, the leaflets are closed to occlude the blood flow.

A method and apparatus for producing a high-velocity particle stream at low cost through multi-staged acceleration using different media in each stage. The particles are accelerated to a subsonic velocity (with respect to the velocity of sound in air) using one or more jets of gas at low cost, then further accelerated to a higher velocity using jets of water. Additionally, to enhance particle acceleration, a vortex motion is created, and the particles introduced into the fluid having vortex motion, thereby enhancing the delivery of particles to the target.

A pharmaceutical comprising a therapeutic protein that binds to a therapeutic target, the protein being modified with a compound that inhibits binding of the protein to the therapeutic target, the modified protein being effective for reducing an immune response against the protein and for producing a therapeutic effect by binding to the therapeutic target. The therapeutic protein may be an antibody that includes an antibody combining site that binds to the therapeutic target.

A novel and useful apparatus for and method of upsampling / interpolating a discrete-time input sample stream with time alignment utilizing the addition of randomized high frequency noise. The upsampling mechanism is an effective implementation of a second order interpolator that eliminates the need for a conventional filter as the filtering action is effectively built into the mechanism. The upsampling mechanism takes the derivative of the discrete-time input sample stream, thereby effectively providing another order of interpolation over a conventional interpolator. Before outputting the interpolated signal, an integrator takes the integral of the interpolated samples. Any processing performed between the derivative and integrator blocks effectively provides an additional order of interpolation. High frequency noise (i.e. dithering) is added to the differentiated samples in order to eliminate the spectral regrowth spurs that would otherwise appear in the output after rounding. Delay alignment is performed on the differentiated samples in order to time align both phase / frequency and amplitude samples that are processed on different paths.

A fully and continuously vented drinking cup or container for infants and children, which consists of a vessel or container for containing a liquid or formula, having a resilient spout which rests upon its uppermost edge. The interior aspects of the feeding spout, and the feeding diaphragm, are all molded so as to arrange the diaphragm slit, or opening through which the liquid flows, in a position that will be vertically aligned between the lips of the infant feeding, to thereby allow the infant to open the spout and allow the liquid to flow, just as if the child is drinking from a cup. The diaphragm may be shaped concavely, with respect to the structure of the feeding spout. A cap firmly approximates the interior aspects of the feeding spout, and applies it to the top or upper edge of the container, whereby a leak proof seal is formed therebetween, but yet allows air to enter between its retaining collar, and the vent tube and reservoir tube, to allow air access into the container, as liquid is being drank therefrom.

When a control circuit detects from a signal CPO4 that a battery voltage is less than a sixth reference voltage, a constant current operation in VFM control is performed with respect to a switching transistor and a synchronous rectification transistor in accordance with signals RVDET and CPO3. Furthermore, when the control circuit detects from the signal CPO4 that the battery voltage becomes equal to or greater than the sixth reference voltage, the constant current operation in PWM control is performed in accordance with a signal CPO2. When an output signal CVDET from a constant current / constant voltage switching detection circuit becomes high level, operation control with respect to the switching transistor and the synchronous rectification transistor is switched from the PWM control of constant current operations to the PWM control of constant voltage operations in accordance with a signal CPO1.

A system for server-side communication support in a distributed computing environment is provided that includes a local reference (202) to a server object (110) on a server system (104). The local reference (202) provides a location of the server object (110) and a type of the server object (110). The local reference (202) resides within a server-side object request broker (114). A type object (204) is accessible by the local reference (202) using the type of the server object (110) from the local reference (202). The type object (204) represents a class of the server object (110). One or more specialized function objects (206) are linked to the type object (204) and correspond in number to one or more methods (190) of the server object (110). The one or more specialized function objects (206) provide wrapper functionality for each method (190) of the server object (110). Each specialized function object (206) provides access to a corresponding one of the one or more methods (190) of the server object (110).

For increasing the film-forming rate and enabling uniform film formation and waste elimination of raw material, a film-forming method and a film-forming apparatus can reach an evaporated film-forming material to a surface of a substrate by the flow of a transport gas so as to control the film-forming conditions by the flow of the gas. Thereby a uniform thin film can be deposited on the large-area substrate. That is, by directing the evaporated raw material toward the substrate, it is possible to increase the film-forming rate and achieve uniform film formation.

A multi-chip module is proposed, which is designed to pack two or more semi-conductor chips in a stacked manner over a chip carrier in a single package. The multi-chip module is characterized by the use of adhesive with fillers to allow the topmost chip (i.e. the second chip) superimposed to the bottommost chip (i.e. the first chip) after the first chip electrically connected to the chip carrier. The thickness of the adhesive layer depends on the diameter of the fillers higher than loop height of the bonding wires that is positioned above the active surface of the first chip to prevent the bonding wires connected to the first chip to come in contact with the overlaid chip.

A pharmaceutical comprising a therapeutic protein that binds to a therapeutic target, the protein being modified with a compound that inhibits binding of the protein to the therapeutic target, the modified protein being effective for reducing an immune response against the protein and for producing a therapeutic effect by binding to the therapeutic target. The therapeutic protein may be an antibody that includes an antibody combining site that binds to the therapeutic target.

A brushless electrical machine, usable as a motor, generator, or alternator, has a rotor that is comprised of a rim portion and a substantially open center portion. The rim portion has a partially hollow core in which a stationary field coil is supported. Current to the field coil generates magnetic flux that circulates in a poloidal flux path in the rim, crossing a single magnetic air gap formed by the rim. Protrusions in the rim located around the circumference form poles all having the same polarity. As the rotor rotates, the flux exiting the poles passes through multiple stationary armature windings around the circumference that are located in the single air gap. An AC voltage is induced in the armature windings from rotation.

A polarizing plate comprising a protective film provided on the both sides of a polarizer, wherein the polarizing plate has an adhesive layer provided on at least one side thereof, which adhesive layer comprising a (meth)acrylic copolymer composition composed of (A) a specific (meth)acrylic copolymer reactive with the following polyfunctional compound (B) and (B) a polyfunctional compound and having a specific gel fraction.

The invention provides a reconfigurable patient support pallet system for transporting patients on litters. The patient support pallet system includes a pallet mounted to the floor of a vehicle. The pallet has a plurality of track rails and attachment points for attaching a litter stanchion set, capable of holding a patient in a litter, and / or for attaching a seat to the surface of the pallet. The pallet also includes a plurality of pallet lips and cargo rings on the periphery which provide locations to attach one or more pallet extensions, pallet spacers and / or pallet ramps to increase the usable surface area of a pallet, as well as facilitate safe passage on, off and between pallets by reducing tripping hazards inherent in cargo aircraft.

An engine ECU executes a program including the steps of: detecting an engine speed NE, engine load, and engine coolant temperature (S100, S110, S115); when determination is made of being in an idle region (YES at S120), determining whether in a cold idle region, a transitional region, or a warm idle region (S130); injecting fuel from an intake manifold injector alone when in the cold idle region (S140); injecting fuel from the intake manifold injector and injecting fuel from an in-cylinder injector at the feed pressure when in the transitional region (S150); and injecting fuel from the in-cylinder injector at the feed pressure when in the warm idle region (S160).

A liquid crystal display device includes a plurality of light emitting diodes mounted on a side wall of a light guide plate so as to irradiate light inside of the light guide plate. On a light reflection surface of the light guide plate, a plurality of light reflection patterns having concentric grooves about the light emitting diodes in the direction equal to the advancing direction of respective main light beams of the light emitting diodes are formed in a state that the plurality of light reflection patterns are divided into a first light reflection pattern region and a second light reflection pattern region respectively corresponding to the light emitting diodes. Between the first light reflection pattern region and a second light reflection pattern region, a light reflection pattern intersecting region where end portions of the light reflection patterns intersect each other is defined.

A method for building a language model, a speech recognition method and an electronic apparatus are provided. The speech recognition method includes the following steps. Phonetic transcriptions of a speech signal are obtained from an acoustic model. Phonetic spellings matching the phonetic transcriptions are obtained according to the phonetic transcriptions and a syllable acoustic lexicon. According to the phonetic spellings, a plurality of text sequences and a plurality of text sequence probabilities are obtained from a language model. Each phonetic spelling is matched to a candidate sentence table; a word probability of each phonetic spelling matching a word in a sentence of the sentence table are obtained; and the word probabilities of the phonetic spellings are calculated so as to obtain the text sequence probabilities. The text sequence corresponding to a largest one of the sequence probabilities is selected as a recognition result of the speech signal.

A coolant cools an object (such as, for example, a coil of a linear motor that drives a stage of an exposure apparatus) while suppressing the generation of a temperature distribution in various parts of the object being cooled by using a coolant that includes a first component and a second component dispersed in the first component, the second component increases in temperature by a lesser amount than the first component when a predetermined amount of heat is absorbed by the first and second components, respectively. The second component may be a substance that changes phase (for example, from a solid to a liquid or from a liquid to a gas) in order to absorb the predetermined amount of heat. The second component may have a higher heat capacity than the first component, and may not change phase when it absorbs heat to cool the object.

The invention relates to a food processor with a rotary type defoaming device. A main body of the food processor comprises a pulverization cutter, a motor, a pulverization knife shaft and a barrel body; a rotary type defoaming device is arranged on the food processor; the rotary type defoaming device comprises a defoamer main body, wherein the rotation center position of the defoamer main body is provided with a shaft center installation hole, or the defoamer main body is provided with a rotating shaft; and the defoamer main body is connected with a power shaft, and the power shaft is the self pulverization knife shaft or other power shafts of the food processor. The invention can actively eliminate foam generated when foods are pulverized, heated and cooked in time, enables the pulverization operation or the heating and cooking operation to be continuously and quickly carried out without intermittent stop, shortens the pulverization or cooking time greatly, enhances the working efficiency, can meet the rhythm of the modern family life and the requirement of quick rhythm of the modern commercial management, enhances the quality of the modern family life and the efficiency of the commercial management obviously and has great economic benefit and social benefit.

A process for producing a porous laminate having many micropores interconnected in the thickness direction, which comprises: a step in which a laminate is produced which comprises at least three layers comprising an interlayer made of a thermoplastic resin having a hard segment and a soft segment and two nonporous outer layers made of a filler-containing resin and located as outer layers respectively on both sides of the interlayer; a step in which the laminate obtained is impregnated with a supercritical or subcritical fluid and this state is relieved to vaporize the fluid and thereby make the interlayer porous; and a step in which the two nonporous outer layers located respectively on both sides are made porous by stretching.

The present invention provides a liquid crystal panel and a liquid crystal display device allowing reliability deterioration due to external pressure to be suppressed without yield rate degradation. The liquid crystal panel includes: a pair of substrates facing each other with a space in between; a liquid crystal layer disposed in the space between the pair of substrates; and a plurality of pairs of pillar structures, each pair of pillar structures being arranged on opposing faces of the pair of substrates, respectively, to face each other along a normal to the opposing faces.