The present invention discloses a terahertz difference frequency source remote active detection system. The system comprises a high-power 1064nm laser, an optical parametric oscillator, a beam delay line, half wave plates, a polarizing beam splitter prism, a gallium selenide crystal, terahertz lenses, a terahertz reflector and a terahertz detector. According to the terahertz difference frequency source remote active detection system of the invention, a high-power terahertz difference frequency source radiation technique is adopted, the quasi-parallel emission-echo focusing technique of the terahertz lens group is used in combination, and therefore, the active detection of the terahertz reflected/scattered signals of a long-distance target can be realized. The terahertz difference frequency source remote active detection system of the invention has the advantages of wide coverage band, high frequency band compatibility, simple structure, high signal-to-noise ratio, long detection distance and the like, and can work under room temperature.