The invention discloses a full-automatic intelligent packer in the technical field of packing devices. The full-automatic intelligent packer comprises a base, a mounting seat, a servo motor, a rotating seat, a clamping unit, a ball screw and a screw nut, wherein the screw nut is sleeved with a floating seat, a lug block is arranged on the floating seat, a sleeve shaft is vertically and rotatably connected to the lug block, the ball screw is driven by an intermittent transmission unit to rotate intermittently, and then the screw nut is driven to drive the floating seat to move vertically. The intermittent transmission unit is arranged to drive the ball screw to rotate, so that after an express packaging box rotates by a circle, the ball screw rotates to drive the lug block to move upwards, adhesive tape placed on the sleeve shaft in an inserted mode can move upwards, then the sealing area of the express packaging box is adjusted, and the sealing effect on the express packaging box is improved. The intermittent transmission unit is composed of a transmission wheel and a driven gear, and when the rotating seat rotates, gear blocks on the transmission wheel can be intermittently in meshing transmission with the driven gear. The structure is simple, the operation is convenient and fast, and the manufacturing cost is reduced.