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The present invention provides methods of administering an insulinotropic peptide in an amount effective to treat a disorder or condition while reducing nausea side effect by administering to a subject in need thereof an insulinotropic peptide conjugated to albumin. The present invention also provides methods of selecting a subject for administration of a conjugated insulinotropic peptide. Exemplary disorders or conditions treatable with an insulinotropic peptide include obesity and type II diabetes.

Satiation devices for controlling obesity and methods of implanting same are configured to create a small satiation pouch in the proximal portion of the stomach with a narrow passage leading into the lower portion of the stomach. The small satiation pouch is configured to collect a small amount of masticated food from the esophagus and the narrow passage delays emptying of the food from the satiation pouch into the larger part of the stomach, thereby causing a feeling of fullness.

The present invention provides methods of administering an insulinotropic peptide in an amount effective to treat a disorder or condition while reducing nausea side effect by administering to a subject in need thereof an insulinotropic peptide conjugated to albumin. The present invention also provides methods of selecting a subject for administration of a conjugated insulinotropic peptide. Exemplary disorders or conditions treatable with an insulinotropic peptide include obesity and type II diabetes.

This invention provides a class of androgen receptor targeting agents (ARTA). The agents define a new subclass of compounds, which are selective androgen receptor modulators (SARM). Several of the SARM compounds have been found to have an unexpected androgenic and anabolic activity of a nonsteroidal ligand for the androgen receptor. Other SARM compounds have been found to have an unexpected antiandrogenic activity of a nonsteroidal ligand for the androgen receptor. The SARM compounds, either alone or as a composition, are useful for a) male contraception; b) treatment of a variety of hormone-related conditions, for example conditions associated with Androgen Decline in Aging Male (ADAM), such as fatigue, depression, decreased libido, sexual dysfunction, erectile dysfunction, hypogonadism, osteoporosis, hair loss, anemia, obesity, sarcopenia, osteopenia, osteoporosis, benign prostate hyperplasia, alterations in mood and cognition and prostate cancer; c) treatment of conditions associated with Androgen Decline in Female (ADIF), such as sexual dysfunction, decreased sexual libido, hypogonadism, sarcopenia, osteopenia, osteoporosis, alterations in cognition and mood, depression, anemia, hair loss, obesity, endometriosis, breast cancer, uterine cancer and ovarian cancer; d) treatment and / or prevention of acute and / or chronic muscular wasting conditions; e) preventing and / or treating dry eye conditions; f) oral androgen replacement therapy; g) decreasing the incidence of, halting or causing a regression of prostate cancer; and / or h) inducing apoptosis in a cancer cell.

To provide a crimped terminal wire for automobile that includes an aluminum electric wire, a connecting terminal made from a copper-based material, and a resin-coated portion that is provided in a range capable of inhibiting crevice corrosion that builds up in a crevice between the connecting terminal and a resin from reaching a bimetal contact portion between the aluminum electric wire and the connecting terminal. A crimped terminal wire for automobile includes an aluminum electric wire, a connecting terminal made from a copper-based material, crimped onto an end of the wire and including a crimped member, a crimped portion where the terminal is crimped onto the wire, and a resin-coated portion disposed on the crimped portion, wherein the resin-coated portion is disposed on the crimped portion while an entire periphery of the crimped portion is coated with the resin-coated portion.

A display apparatus includes: a plurality of pixels coupled to gate lines and to data lines configured to cross the gate lines, a gate driver configured to apply gate signals to the gate lines, a first data driver configured to apply first data voltages to first signal lines, a first DEMUX part configured to selectively couple the first signal lines to the data lines, a second data driver configured to apply second data voltages to second signal lines positioned to correspond to the first signal lines, and a second DEMUX part positioned to face the first DEMUX part such that the pixels are positioned between the first and second DEMUX parts, the second DEMUX part configured to couple the second signal lines to the data lines, which are not coupled to the first signal lines. Each of the first data voltages has a polarity opposite to a polarity of a corresponding second data voltage of the second data voltages.

According to the present invention, a set of an automatic lifting device and automatic inclination adjusting device is arranged beside the external container truck parking lane of an automated terminal, a laser scanner is arranged on the automatic lifting device and automatic inclination adjusting device, and performs lifting and inclining detection on the locking holes of a no-load container flatcar entering the lane, the position of the nearest locking hole or the positions of the multiple locking holes are measured, the approximate positions of all the locking holes on the container flat car are estimated, and accurate detection is performed to find the exact positions of all the locks, such that the precise positioning of the container flat car is achieved; the laser scanner horizontally scans the heavy-load container truck entering the lane, and adjusts the automatic lifting device to a corresponding height according to the lifting tool positioning signal and the lifting tool height signal, the gap between the container and the flat car is measured, the unlocking of the lock of the container truck is prevented, and the container truck is lifted; and with the method of the present invention, the precise lock positioning and anti-lifting detection of the external container truck in the lifting yard of the automated field can be achieved.

A process for separating IC dies from a wafer substrate. In one embodiment, complete separation channels are initially cut through the wafer between dies along one axis. Next, partial separation channels are cut into the wafer along an intersecting axis, leaving wafer material connecting adjacent dies. In another embodiment, partial separation channels are cut into the wafer along one axis, after which complete separation channels are cut through the wafer along the intersecting axis. In still another embodiment, partial separation channels are cut along both axes.

This invention provides a class of androgen receptor targeting agents (ARTA). The agents define a new subclass of compounds, which are selective androgen receptor modulators (SARM). Several of the SARM compounds have been found to have an unexpected androgenic and anabolic activity of a nonsteroidal ligand for the androgen receptor. Other SARM compounds have been found to have an unexpected antiandrogenic activity of a nonsteroidal ligand for the androgen receptor. The SARM compounds, either alone or as a composition, are useful for a) male contraception; b) treatment of a variety of hormone-related conditions, for example conditions associated with Androgen Decline in Aging Male (ADAM), such as fatigue, depression, decreased libido, sexual dysfunction, erectile dysfunction, hypogonadism, osteoporosis, hair loss, anemia, obesity, sarcopenia, osteopenia, osteoporosis, benign prostate hyperplasia, alterations in mood and cognition and prostate cancer; c) treatment of conditions associated with Androgen Decline in Female (ADIF), such as sexual dysfunction, decreased sexual libido, hypogonadism, sarcopenia, osteopenia, osteoporosis, alterations in cognition and mood, depression, anemia, hair loss, obesity, endometriosis, breast cancer, uterine cancer and ovarian cancer; d) treatment and / or prevention of acute and / or chronic muscular wasting conditions; e) preventing and / or treating dry eye conditions; f) oral androgen replacement therapy; g) decreasing the incidence of, halting or causing a regression of prostate cancer; and / or h) inducing apoptosis in a cancer cell.

An ergonomic, contoured urinal floor mat for use with wall-urinals with the purpose of positioning a user center, up and toward a wall-urinal so as to prevent urine spillage and drippings from reaching floor below a wall-urinal. The floor mat consists of a heavy duty, permanent material with topside anti-slip and floor conforming anti-skid surfaces and is designed with three unique contouring angles which, in combination, elevates heels above toes, spreads legs, pushes toes outward, pulls heels inward, and creates a lift in the inner arch of the foot. The system also incorporates a replaceable drip tray, located between the users' legs and the urinal lip (to catch the inevitable last drops), a topside perimeter gutter (for complete urinal misses), and underside seal (to prevent liquids seepage under mat). If spills do occur, the overall contouring guides liquid into the gutter and keeps the topside foot areas dry.

A security policy enables security devices to forward ICE messages. The security policy may use protection tokens to prevent Denial of Service (DoS) attacks. This allows endpoints to use Interactive Connectivity Establishment (ICE) to enable multimedia communications across Network Address Translators (NATs) and other security devices.

The invention discloses a method and a device for detecting a user head-lowering posture, and is applied to intelligent handheld devices. The method comprises the following steps: judging whether the user head-lowering posture is abnormal or not; if the user head-lowering posture is abnormal, reminding the user of the abnormity of the head-lowering posture to request the user to adjust the head-lowering posture and open a timer; performing voice announcement on the user if the timer is overtime and the user does not adjust the head-lowering posture; setting the intelligent handheld device into a non-working mode after the voice announcement is ended.

An antireflection film that has sufficient antireflection capability and antifouling property and is improved in scratch resistance, and a process for producing an antireflection film with considerably high productivity are provided, which is an antireflection film comprising a transparent support, a hard coat layer and a low refractive index layer, in this order, wherein the hard coat layer includes a polymerized product of (A) an ethylene oxide or propylene oxide adduct of a polyfunctional acrylate monomer and (B) a polyfunctional acrylate monomer having no oxide adduct.

A vitreous silica crucible manufacturing apparatus includes a plurality of carbon electrodes configured to heat and melt raw material powder by arc discharge, and a value of a ratio R2 / R1 of a diameter R2 of a front end of each of the carbon electrodes to a diameter R1 of a base end is set in a range of 0.6 to 0.8. Each carbon electrode has a diameter reduction portion formed at a front end position and reduced in diameter from a diameter R3 of a base end side to the diameter R2 of the front end. When a length of the diameter reduction portion is L1, the diameter of the front end is R2, the diameter of the base end is R1, an angle between the axis lines of the carbon electrodes is θ1, and X=(R1−R2) / 2, a value of L1−(X / tan(θ1 / 2)) is set in a range of 50 to 150 mm.

A system for controlling administration of a respiratory depressant drug or mixture of drugs to a spontaneously breathing patient comprises a drug delivery unit (3), being adapted for indexed or continuous and automatic titration of a respiratory depressant drug or mixture of such drugs to said patient (1), and a control apparatus (6), receiving measurement signals (20) relative to the respiratory state of said patient (1) and issuing control signals (27) to said drug delivery unit (3), wherein the control apparatus is adapted to keep said measurement signals relative to the respiratory state to a predetermined condition and thereby providing adequate sedation and / or analgesia to said patient.

An eccentricity correction data recording method, a disk-shaped recording medium, a head position control method and an information recording and reproducing apparatus are disclosed for effective eccentricity correction on cylinders of a disk-shaped recording medium. The eccentricity correction data recording method is for position control over a recording and reproducing head on a disk-shaped recording medium having at least one user data recording area to record user data, the method including the step of recording the eccentricity correction data in a user data recording area.

A phantom and film cassette therefor, a composition of high atomic number elements and tissue-equivalent material for a phantom, and an adjustable holder for a phantom. The film cassette comprises sections of tissue-equivalent material, wherein the sections retain a sheet of film when closed together and the phantom composition comprises tissue-equivalent material and high atomic number elements. In operation, dose distributions are determined via computation at various depths within a simulated water-equivalent phantom. After calculating dose distributions, an actual beam is delivered to a phantom containing the cassette, or utilizing a phantom containing high atomic number elements, wherein the phantom mimics human tissue, wherein the phantom houses radiographic film. Images are then generated on the film, the images are converted into an actual dose distribution, and the actual dose distribution is compared with the calculated dose distributions. Finally, a patient is treated based on the beam delivery thus verified.

A computer implemented method and data processing system are provided for preventing firmware defects from disrupting logic clocks. In response to a firmware interface requesting a scan operation for a functional unit, protection logic allows a scan enable to activate to the functional unit only if the logic clocks are stopped to that functional unit, otherwise the scan enable is not activated, an error is indicated, and an interrupt is presented to firmware. Also, in response to a command from a firmware interface to stop the logic clocks to a functional unit, protection logic allows the clocks to be stopped to the functional unit only if the functional unit is already indicating a catastrophic error, otherwise the clocks are not stopped, an error is indicated, and an interrupt is presented to firmware.

Disclosed is a method of making a flat panel display device. The device has a first substrate, a second substrate opposing the first substrate and an array of pixels formed therebetween. A frit is interposed and interconnects between the first substrate and second substrate. The frit is melted by irradiating a first laser and a second laser. The first and second lasers move along the different paths.

A flat panel display includes: a substrate that includes a display region and a non-display region at a periphery of the display region; a pixel array disposed on the substrate of the display region; an input pad part disposed on the substrate of the non-display region; a bonding pad part disposed on the substrate of the non-display region, the bonding pad part including a plurality of output pads connected to the pixel array and a plurality of input pads connected to the input pad part; and a protective layer disposed on the substrate of the non-display region, the protective layer having openings formed therein that expose portions of the bonding pad part and the input pad part, wherein the opening of the protective layer is smaller than the bonding pad part, wherein the protective layer is thinner at a portion that overlaps the bonding pad part than at other portions.

A fully portable exercise system and apparatus utilized for exercising, stretching, and training multiple muscle groups of the body of a user. The apparatus has at least one closeable pocket and fixation rings for securing and carrying accessories, such as attachable handgrips, adjustable suspension straps or lines, and elastic bands. Another configuration illustrates a suspension training system comprising non-elastic suspension sub-assemblies, elastic suspension sub-assemblies and handgrips, configurable with or without the portable exercise apparatus. The apparatus and methods of use provide the user with a plurality of configurations for assisted exercise regimens and the flexibility to exercise anywhere. The apparatus is adaptable to be worn about the waist of a user, carried as a bandolier about the user's body or utilized as a releasably fixed suspension trainer.

A display device for overlaying encoded steams includes a decoder within the display device for decoding a primary encoded stream and a secondary encoded stream to produce a primary unencoded stream and a secondary unencoded stream including secondary information and overlay information. The display device includes an overlay controller for combining the primary unencoded stream and the secondary unencoded stream to produce a composite stream. The display device includes a display adapted to display images corresponding to the composite stream, the images including a primary image corresponding to the primary unencoded stream and a secondary image corresponding to the secondary information overlaid on the primary image corresponding to the overlay information.

The invention relates to a drum winch (100) that is arranged to allow “free fall” of an anchor secured by rode to a drum (116) of the drum winch (100). The drum winch (100) includes a mounting bracket (112) and a drive shaft (114) arranged to be mounted to the mounting bracket (112) and coupled to the drive unit (118). The drum (116) is arranged relative to the drive shaft (1114) so that in a first mode of operation of the drum winch (100), the drum (116) can be rotated by rotation of the drive shaft (114). In a second mode of operation of the drum winch (100), the drum (116) is free to rotate relative to the drive shaft (114) so as to enable “free fall” of the anchor. The drum winch (100) further includes means for actuating (150) either the first mode of operation or the second mode of operation.

Wood is treated with a film-forming silicone emulsion composition, a boron compound, and a di- or trivalent metal salt. The wood can be endowed with water repellency, water absorption prevention, dimensional stability, termite control and antifungal properties without altering the appearance and quality of wood. The treatment is also effective in preventing the boron compound from being leached out in water.

A vehicle control system configured to carry out an energy saving control is provided. The vehicle control system is applied to a vehicle having an engine, a torque converter, a transmission and a clutch device selectively connecting a turbine runner to the transmission. The vehicle control system executes the energy saving control by controlling both an operating condition of the engine and an engagement condition of the clutch device or only the engagement condition of the clutch device. The vehicle control system comprises a clutch control means configured to increase the torque transmitting capacity of the clutch device using an increasing amount of a speed of the turbine runner as a target value, when bringing the clutch device into engagement being in disengagement during execution of the energy saving control.

A thin film transistor array panel includes a substrate; a data line disposed on the substrate; a buffer layer disposed on the substrate and spaced apart from the data line in a plan view; a thin film transistor disposed on the buffer layer, the thin film transistor including an oxide semiconductor layer; and a pixel electrode connected to the thin film transistor.

The invention relates to microbiology and medicine and can be used to prevent and treat diseases and conditions associated with disruption of normal (autochthonous) microflora (microbiota) in humans or animals. In particular, a solution for recovery or creation of the subject's microflora comprising an active component containing microorganisms isolated from the microflora of the subject or the donor, wherein the active component can be enriched with bacteriophages of said microflora and / or additional microorganisms of the microflora cultivated on a nutrient medium, while the additional microorganisms of the microflora include microorganisms of the microflora that are yet nonculturable in the absence of the host organism, is proposed. Also provided are a pharmaceutical dosage form comprising the above solution and methods for prevention or treatment of diseases and / or conditions associated with and / or accompanied by a disorder or lack of the subject's own microflora, comprising administering the solution or pharmaceutical dosage form.

A heat dissipation module including a supporting frame, a driver, a linkage, a first magnet and a plurality of magnetic blades is provided. The supporting frame has a chute. Moreover, one end of the linkage has a protrusion passing through the chute. The other end of the linkage is connected to the driver. The first magnet is disposed on the protrusion. In addition, the repelling magnetic blades are pivoted on the supporting frame. The outermost magnetic blade faces the first magnet and they repel each other.