The invention discloses a portable high-efficiency pesticide spraying device, which comprises a spraying vehicle body, a chemical storage spraying mechanism arranged on the top of the chemical spraying vehicle body, a spraying frame mechanism installed on the left end surface of the chemical spraying vehicle body, and a chemical storage spraying mechanism. It is composed of a medicine storage box and a spray pump. The medicine storage box is rotated and connected with a downwardly extending stirring shaft. The spraying body below the medicine storage box is provided with a first sliding chamber, and the bottom end of the stirring shaft extends into the first The first cone wheel is fixed in the sliding chamber and at the end, and the first sliding block is slidably connected to the first sliding chamber on the right side of the first cone wheel, and the first motor is provided in the left end surface on the upper side of the first sliding block The left side of the first motor is mated with a second cone wheel that extends out of the left end face of the first sliding block and is used to cooperate with the first cone wheel. The spraying body below the first slide chamber is provided with a second Motor; the present invention is simple in structure, easy to operate, convenient to disassemble and install, convenient to move, carry and maintain, saves time and effort, stirs evenly, and improves work efficiency.