The invention provides a production method of a super-hydrophobic polytetrafluoroethylene membrane. The method comprises the steps of preparing a spinning solution, producing fibers, and sintering, wherein a fiber forming carrier and a solvent are adopted to prepare a solution, a polytetrafluoroethylene emulsion is added, the fiber forming carrier is polyacrylic acid, and the solvent is water; and the sintering step adopts temperature programmed control sectional continuous sintering, and is characterized by carrying out heat insulation in flowing atmosphere at 90-120DEG C for 30-120min, heating to 260-300DEG C from 90-120DEG C at a rate of 3-10DEG C/min, carrying out heat insulation at 260-300DEG C for 30-120min, heating to 370-390DEG C from 260-300DEG C at a rate of 2-8DEG C/min, and carrying out heat insulation at 370-390DEG C for 5-120min. The method well solves the problem of easy collapsing of fibers in the sintering process of a polytetrafluoroethylene precursor membrane, and allows the beaded ultrafine fiber netted membrane, disordered stacking between fibers becomes mutual adhesion, and the fibers have the characteristics of uniform form, complete surface, and greatly improved strength and toughness, and can bear a certain vacuum pressure.