The invention discloses an anti-collision knife numerical control machine tool, comprising a machine tool body, an x-axis motor, an x-axis screw, a y-axis screw, a y-axis motor, a z-axis slide rail, a z-axis screw, a fixing frame and a fourth motor , shell, fixture, collection trolley and anti-collision tool device, the built-in milling cutter in the fixture accidentally hits the support plate downwards during the debugging process, and under the action of the spring force, the support plate slides down to provide buffering for the built-in milling cutter in the fixture , to prevent the built-in milling cutter of the fixture from directly hitting the built-in milling cutter of the fixture and cause the cutter to break and damage. After the debugging of the CNC program is completed, the fifth motor starts to rotate forward, so that the fourth screw rod moves upward, and the connection block at the top is attached to the limit. The bottom end face of the block is used to fix the top support plate. During the deep hole machining of the workpiece, the workpiece will sink under the action of the spring force, which will cause the spring to buffer the workpiece and cause workpiece accuracy errors. This device fixes the support plate to avoid The machining error of the workpiece is affected by the spring force during the machining process.