104 results about "Hemoglobin levels" patented technology

In certain aspects, the present invention provides compositions and methods for increasing red blood cell and/or hemoglobin levels in vertebrates, including rodents and primates, and particularly in humans.

In certain aspects, the present invention provides compositions and methods for increasing red blood cell and/or hemoglobin levels in vertebrates, including rodents and primates, and particularly in humans.

This invention provides aryl and heteroaryl compounds of Formula (I) as described herein, and methods of their preparation. Also provided are pharmaceutical compositions made with the compounds of Formula (I) and methods for making such compositions. The compounds of Formula (I) may activate an erythropoietin receptor and thus, may be useful to induce red blood cell production. The compounds of Formula (I) and compositions including compounds of Formula (I) may be useful in a variety of applications including the management, treatment and/or control of diseases caused at least in part by deficient (or inefficient) EPO production relative to hemoglobin level.

In certain aspects, the present invention provides compositions and methods for increasing red blood cell and/or hemoglobin levels in vertebrates, including rodents and primates, and particularly in humans.

The present invention relates to a testing system for assessing hypoxia induced cellular damage in a mammal including human, comprising a disposable device having a sample inlet and a collection chamber separated by a separation device wherein the collection chamber is connected to at least two, a first and a second, visible detection compartments, whereof at least one is arranged with chemical means for direct visual detection, said first detection compartment being arranged to determine whether level of hemoglobin (Hb) in a sample of body fluid taken from said mammal exceeds a predetermined threshold value, and said second detection compartment being arranged to evaluate level of total amount of lactate dehydrogenase (LDH) in said sample.

Systems, methods, and related computer program products for non-invasive NIR spectrophotometric (NIRS) monitoring of total blood hemoglobin levels and/or other blood constituent levels based on a hybrid combination of phase modulation spectrophotometry (PMS) and continuous wave spectrophotometry (CWS) are described. PMS-based measurements including both amplitude and phase information used in the determination of a non-pulsatile component of an absorption property for each of at least three distinct wavelengths are processed to compute PMS-derived intermediate information at least partially representative of a scattering characteristic. CWS-based measurements including amplitude information is processed in conjunction with the PMS-derived intermediate information to compute a pulsatile component of the absorption property. A metric representative of at least one chromophore level, such as the total blood hemoglobin level, is computed from the pulsatile component of the absorption property at the at least three wavelengths and displayed on an output display.

In certain aspects, the present disclosure provides compositions and methods for increasing red blood cell and/or hemoglobin levels in vertebrates, including rodents and primates, and particularly in humans. In some embodiments, the compositions of the disclosure may be used to treat or prevent sickle-cell disease or one or more complications associated with sickle-cell disease.

The present disclosure provides compositions and methods for treating or preventing ulcers in subjects having low red blood cell levels and/or hemoglobin levels (e.g, anemia). In some embodiments, the compositions of the disclosure may be used to treat or prevent ulcers associated with anemia.

The present invention pertains to a hemolysis sensor, a hemolysis sensor system and methods of utilizing the hemolysis sensor or hemolysis sensor system to monitor or detect hemolysis in a sample, such as a whole blood sample, a plasma sample, a serum sample or hemolyzed blood. The hemolysis sensor responds to extracellular hemoglobin levels, for example, extracellular hemoglobin in a whole blood sample as a method for detecting hemolysis in whole blood.

The invention provides engineering rice suitable for people having unbalanced diet and with a function of reducing blood glucose and a preparation method of the engineering rice. The invention relates to the engineering rice suitable for people suffering from hyperglycemia caused by unbalanced nutritional structure and the preparation method of the engineering rice. The engineering rice comprises pumpkin powder, brown rice powder, inulin, konjac gum, fishskin peptide, oat fiber, soybean protein isolate, beta-carotene and lecithin. The engineering rice is prepared by the following steps: premixing the raw materials; performing high-temperature high-pressure texturizing forming by using a double screw extruder; and drying, dedusting and packaging to obtain the engineering rice. The engineering rice has low glycemic index and low cholesterol content, has the effects of stabilizing postprandial blood glucose, improving insulin resistance and effectively improving glucose tolerance, glycosylated hemoglobin level and the like, and is suitable for people suffering from metabolic syndrome caused by diabetes.

The present invention provides a new subcutaneous injection dosing regimen for erythropoietin to treat anemia. The new erythropoietin treatment regimen of the present invention results in improved hemoglobin levels with less frequent dosing.

In certain aspects, the present disclosure provides compositions and methods for increasing red blood cell and/or hemoglobin levels in vertebrates, including rodents and primates, and particularly in humans. In some embodiments, the compositions of the disclosure may be used to treat or prevent sideroblastic anemias and myelodysplastic syndromes or one or more complications associated sideroblastic anemias and myelodysplastic syndromes.

The present invention relates to a cell culture medium for culturing human cells comprising an anti-coagulated total blood material wherein the hemoglobin level is from about 8 to about 16 g/dl. More particularly, the invention provides a cell culture medium in which cells present in the blood are disrupted and the insoluble remnants of the lysated cells are removed. Further, the invention provides a method for the preparation of a cell culture medium for culturing human cells, according to the invention.

The device enables measurement of both of blood glucose level and hemoglobin A1c level, being small-sized and thus portable, allowing the measurement of a small amount of a specimen and, being usable in POC. The device comprises: a test-piece-mounting section (1) for detachably mounting test pieces (200) on which the blood specimen is to be spotted; a light-emitting section (2) for emitting light for irradiating the test pieces; a light-receiving section (3) for receiving reflected lights from the test pieces; and an operating section (4) for calculating the blood glucose level and hemoglobin A1c level of the blood specimen on the basis of photometric values obtained from the light-receiving section. For measuring the blood glucose level of the blood specimen, test piece (A) carries a composition reacting with glucose and showing color change. Test piece (B) carries a composition reacting with glycated hemoglobin and showing color change.

The invention provides a detection method, which is used for detecting blood glucose level and hemoglobin level used for detecting a blood sample. The method comprises the following steps: applying first voltage on the blood sample, taking a first blood sugar level; applying second voltage on the blood sample, taking a second blood sugar level; applying third voltage on the blood sample, collecting a hematocrit index and a hemoglobin index; transferring the hematocrit index to the hematocrit level, correcting the second blood sugar level by the hematocrit level; and transferring the hemoglobin index to the hemoglobin level. The method can be used for simultaneously detecting the blood glucose level and hemoglobin level used for detecting the blood sample on a single detector by using a single test piece.

The invention discloses applications of firmicute probiotics in preventing and/or treating diabetes and relevant diseases, specifically, the firmicute probiotics are used or preparing a composition or a preparation. The composition or the preparation has the following one or more applications: (1) preventing and/or treating diabetes; (b) preventing and/or treating cardiovascular diseases; and/or (c) preventing and/or treating obesity. The firmicute probiotics can obviously inhibit the weight increase, reduce the serum glucose level, reduce the blood lipid level, improve the insulin resistance and/or reduce the glycosylated hemoglobin level, and thus the symptoms of diabetes and relevant diseases can be effectively alleviated.