The invention discloses an unmanned ship position and speed estimation structure and a design method. The structure comprises an accelerometer unit, a gyroscope unit, a magnetometer unit, a global positioning system signal acquisition unit, a coordinate system conversion unit, a state recombining unit, a comparing unit, an inertia navigation system data resolving unit and a nonlinear observer navigation filtering algorithm unit. According to the unmanned ship position and speed estimation structure disclosed by the invention, the unmanned ship position and speed information containing measurement noise is utilized, multi-sensor information fusion treatment is performed through a method based on a nonlinear observer, and actual unmanned ship position and speed information can be estimated;thus, not only is the convergence characteristic of the designed nonlinear observer is more accurate, but also convenience is brought to a parameter adjusting process, and the calculated amount is reduced. According to the unmanned ship position and speed estimation structure disclosed by the invention, the problem of measurement noise of the sensor is taken into consideration, the actual positionand speed information can be obtained from the state information with the measurement noise, more continuous and more stable navigation data can be formed, and estimation of a course angle can be more accurate.