A traditional Chinese medicine for treating chronic lymphocytic thyroiditis, comprising 10-20g of Bupleurum bupleuri, 15-20g of angelica, 13-18g of white peony root, 15-20g of Rhizoma Cyperi, 10-20g of Prunella vulgaris, 10-20g of Zhebei, It is prepared from 10-15g of vaccinia, 15-20g of seaweed, 13-16g of kelp, and 10-20g of tangerine peel. The present invention has good curative effect, strong practical pertinence, and small side effects; the traditional Chinese medicine compound has been proved to reduce the level of serum thyroid autoantibodies in patients with chronic lymphocytic thyroiditis and animal models through previous large-scale clinical observation and animal experimental research, and reduce the level of thyroid tissue lymphocytes. Infiltration, inhibition of thyroid cell apoptosis and other multi-target effects, the curative effect is definite. The invention uses traditional Chinese medicine to treat both subclinical and clinical stages of chronic lymphocytic thyroiditis and plays a good role, has great application market potential and good prospects, and will surely produce good economic and social benefits.