The invention discloses a large-power air coupling ultrasonic vibration transducer which comprises a bolt, a back shroud, a piezoelectric ceramic piece, an electrode piece, an amplitude transformer, a conversion sleeve, a vibrating plate and a coupling layer, wherein the coupling layer is stuck to the vibrating plate. The back shroud, the piezoelectric ceramic piece, the electrode piece and the amplitude transformer are sleeved on the bolt in sequence, the back shroud and the amplitude transformer clamp the piezoelectric ceramic piece and the electrode piece tightly through the bolt, the conversion sleeve is arranged at the front end of the amplitude transformer, and the vibrating plate and the coupling layer which is stuck to the vibrating plate are arranged at the front end of the conversion sleeve. The large-power air coupling ultrasonic vibration transducer uses a sandwich type piezoelectric transducer structure and has the advantages of being large in power capacity, high in sound field output strength and the like. The large-power air coupling ultrasonic vibration transducer can be applied to the fields of ultrasonic defoaming, ultrasonic suspension, ultrasonic medical treatment, ultrasonic dedusting, ultrasonic drying, ultrasonic gas medium sound field focusing, multi-phase sound field focusing, ultrasonic coagulation, ultrasonic nondestructive testing and the like.