The invention provides a shaft transmission mechanism of a motorcycle, and belongs to the technical field of motorcycles. The shaft transmission mechanism of the motorcycle solves the technical problems that in a current shaft transmission mode of the motorcycle, after a 
clutch friction disc and a steering 
assembly are matched, the axial size, along a power input rod, of a whole formed by the 
clutch friction disc and the steering 
assembly is relatively large, and the problem exists that the structure is not compact enough. The shaft transmission mechanism of the motorcycle includes a speed changing mechanism, a transmission shaft and a driving rear axle, the transmission shaft extends along the front-rear direction of a motorcycle body, an output shaft extends along the left-right direction of the motorcycle body and penetrates through a speed changing shell, the outer end portion of the output shaft is connected with an input 
bevel gear in a sleeved mode, the periphery of the other end of the transmission shaft is connected with a driven shaft in a sleeved mode, the driven shaft is connected with an output 
bevel gear in a sleeved mode, the input 
bevel gear and the output bevel gear mesh with each other, a four-
point contact ball bearing is arranged between the input bevel gear and the speed changing shell, the four-
point contact ball bearing is sleeved on the periphery of the output shaft, and the inner end of the outer ring of the four-
point contact ball bearing abuts against the speed changing shell. The shaft transmission mechanism of the motorcycle has the advantages of being less in space 
wasting and compact in structure.