The invention provides a voice control method of an application program, an intelligent terminal and a computer readable storage medium. The voice control method of the application program comprises the following steps: S100, analyzing the display interface of the intelligent terminal running the application program; S200, identifying the program contents in the display interface; S300, constructing a content model based on the program content, and determining an operation unit within the program content according to the content model; S400, the application program collecting a speech input; S500, according to the preset modulation parameter, converting the second speech parameter of the speech input into the first speech parameter of the operation unit; S600, playing a voice input havinga first voice parameter. Through adoption of the technical scheme, the speech input by the user is recognized and automatically converted into the speech of the current operation character of the user, and when the speech is output to other users, the privacy can be improved by hiding the real sound, the gameplay of the application program can be more simulated, and the user experience can be improved.