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1 results about "Lymphocyte activation" patented technology

Lymphocyte activation. the stimulation of lymphocytes by antigens or mitogens, rendering them metabolically active and causing them to differentiate into effector cells.

An atrial fibrosis targeting adjuvanted influenza vaccine composition for patients with atrial fibrillation

PendingCN122272787Aavoid infectionactivate specific immune responseHemagglutininDendritic cell
This invention discloses a targeted adjuvant influenza vaccine composition for atrial fibrillation patients with atrial fibrosis. The vaccine antigen components are selected from the surface antigens of currently prevalent influenza virus strains, such as hemagglutinin (HA) and neuraminidase (NA). High-purity influenza virus antigens are prepared through cell culture or recombinant DNA technology. For example, influenza virus is cultured using Madin-Darby canine kidney (MDCK) cells, and purified through centrifugation, filtration, and chromatography to obtain high-purity HA and NA antigens. After injection into the human body, the influenza virus antigens (HA and NA) are taken up and processed by antigen-presenting cells (such as macrophages and dendritic cells). The antigen-presenting cells present antigen peptides to T lymphocytes and B lymphocytes, activating a specific immune response. B lymphocytes differentiate into plasma cells with the help of T lymphocytes, producing specific antibodies that recognize and bind to the influenza virus, preventing it from infecting host cells and thus preventing influenza virus infection.
Owner:FUJIAN MEDICAL UNIV UNION HOSPITAL