A portable pressure calibrator used in cooperation with a breathing machine relates to a detection device and comprises folding supports, the folding supports are symmetrically arranged on the breathing machine, buckle seats are arranged in the folding supports, a main rack is arranged on the buckle seats, the buckle seats are symmetrically arranged on the main rack, and a central control display screen is arranged in the main rack. A central control unit is arranged at the bottom of the central control display screen and is connected with the central control display screen through an electronic element, the central control unit is arranged in the main frame, a wireless slave station is arranged in the main frame and is in sliding connection with the main frame, and a wired slave station is arranged in the main frame and is in sliding connection with the wired slave station. By means of the device, random debugging in the calibration operation process is facilitated through the arrangement of the handle device, meanwhile, the device can be fixed to the breathing machine through the support, and equipment loss is avoided; a master-slave station integrated mode is adopted, so that matching use and carrying with the breathing machine are facilitated; through wired and wireless two-end slave station communication acquisition, data accuracy is facilitated, and signal interference does not occur at the same time.