The invention discloses a spatial arrangement method of a pipe network pipe explosion monitoring network. The spatial arrangement method comprises the steps that basic data collection and analysis are conducted, specifically, a plurality of pressure and flow monitoring devices are arranged in a pipe network, and the fluctuation degree of the pressure and the flow in the pipe network is analyzed through data extraction; pipe explosion analysis is conducted, specifically, a hydraulic model is built, the impacting degree of pipe explosion on the pipe network is analyzed, and whether pipe explosion impacting exceeds the normal fluctuation amplitude of the pipe network is judged; and monitoring network optimization is conducted, specifically, the explosive leakage quantity is monitored as much as possible to build the monitoring network optimization function to conduct spatial optimization, the number of monitoring points is gradually increased to enable the pipe explosion monitoring coverage rate to be increased by the amount less than a certain amount and then stop. According to the spatial arrangement method of the pipe network pipe explosion monitoring network, the complete arrangement method of the pipe explosion monitoring network is built, through analysis of natural fluctuation of a pipe network, it is ensured that with pipe explosion impacting being captured by the monitoring network as the goal, spatial arrangement and number control of the monitoring network are reasonably conducted, and pipe network pipe explosion emergency early warning can be economically, reasonably and efficiently provided.